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GlossaryCaveolin-1

protein involved in cell membrane structure and signaling

Caveolin-1 (CAV1) is a protein that plays a crucial role in the formation of caveolae, which are small invaginations on the cell membrane involved in various cellular processes such as signal transduction and endocytosis. It is also important in regulating lipid metabolism and maintaining cellular structure. In the context of hair biology, alterations in Caveolin-1 expression have been linked to conditions like alopecia, where hair loss occurs.

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Deregulation of Toll Like Receptor Signaling and Association With Caveolin-1 in Lichen Planopilaris Reveals a Novel Mechanism in Pathogenesis of Scarring Alopecia

research Deregulation of Toll Like Receptor Signaling and Association With Caveolin-1 in Lichen Planopilaris Reveals a Novel Mechanism in Pathogenesis of Scarring Alopecia

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

The study suggests that changes in immune system receptors and their interaction with a cell component may be important in the development of a type of hair loss condition.

research Comprehensive Transcriptome Data to Identify Downstream Genes of Testosterone Signaling in Dermal Papilla Cells

November 2022 in “Scientific Data”

The research identified genes and non-coding RNAs in cells that could be affected by testosterone, which may help understand hair loss and prostate cancer.

research Comparative Transcriptome Profiling of Hair Follicles from Forest Musk Deer at Different Stages

November 2022 in “Research Square (Research Square)”

The research provides insights into hair follicle growth in forest musk deer by identifying key genes and pathways involved.

Spatial Transcriptomic Analysis of Imiquimod-Treated Mouse Skin Reveals Deregulation of Lipid Raft-Associated Markers Reversible by Caveolin Scaffolding Domain Peptide

research Spatial Transcriptomic Analysis of Imiquimod-Treated Mouse Skin Reveals Deregulation of Lipid Raft-Associated Markers Reversible by Caveolin Scaffolding Domain Peptide

April 2023 in “Journal of Investigative Dermatology”

The research found that a protein called caveolin-1 is reduced in psoriasis, but reintroducing it can help alleviate some psoriasis symptoms.

A Cell Membrane-Level Approach to Cicatricial Alopecia Management: Is Caveolin-1 a Viable Therapeutic Target in Frontal Fibrosing Alopecia?

research A Cell Membrane-Level Approach to Cicatricial Alopecia Management: Is Caveolin-1 a Viable Therapeutic Target in Frontal Fibrosing Alopecia?

4 citations , May 2021 in “Biomedicines”

Targeting the protein Caveolin-1 might help treat a type of scarring hair loss called Frontal Fibrosing Alopecia.

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