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Effect of a Non-Ionic Surfactant on Skin Retention of Cationic Minoxidil Microparticles Suspended in an Anionic Surfactant Solution

research Effect of a non-ionic surfactant on skin-retention of cationic minoxidil microparticles suspended in an anionic surfactant solution

2 citations , November 2009 in “Korean journal of chemical engineering”

This study found that the nonionic surfactant Brij 78 stabilized cationic minoxidil microparticles against aggregation, maintaining their substantivity in the presence of excess anionic surfactant.

research Substantivity and After‐Rinsing Hair Growth Promotion of Cationic Microparticles of Minoxidil

2 citations , April 2008 in “Journal of Dispersion Science and Technology”

This study observed that including cationic minoxidil particles in a shampoo facilitated notable hair growth promotion despite a negative surface charge after rinsing, likely due to ionic interactions with the skin.

In Vivo Hair Re-Growth Efficacies of Minoxidil Preparations: Distearyldimethylammonium Chloride Vesicles, Cellulose Acetate Phthalate Microparticles, and Poloxamer Solution

research In vivo hair re-growth efficacies of minoxidil preparations: distearyldimethylammonium chloride vesicles, cellulose acetate phthalate microparticles, and poloxamer solution

2 citations , January 2009 in “Journal of Drug Delivery Science and Technology”

This study found that cationic vesicles enhanced minoxidil skin retention and in vivo hair growth efficacy compared to other formulation types due to electrostatic interactions with the skin.

research Iontophoresis of minoxidil sulphate loaded microparticles, a strategy for follicular drug targeting?

25 citations , July 2015 in “Colloids and Surfaces B: Biointerfaces”

This study found that microencapsulation combined with iontophoresis can significantly enhance the delivery of minoxidil sulphate to hair follicles, suggesting a synergetic approach for topical drug targeting.

research Chitosan nanoparticles for targeting and sustaining minoxidil sulphate delivery to hair follicles

77 citations , January 2015 in “International Journal of Biological Macromolecules”

This study developed minoxidil sulphate-loaded chitosan nanoparticles that doubled drug delivery to hair follicles in vitro compared to a control solution, suggesting potential for improved alopecia treatment.

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7 / 801 results

learn Minoxidil

An essential vasodilator with some anti-androgenic effects

Minoxidil 2%, 5% and 10% which is better to use? In a randomized trial in men, 5% topical minoxidil produced more hair growth than 2%. There is no approved 10% product and no head-to-head trial showing it beats 5%; higher strengths mainly add irritation and systemic absorption. Approved strengths differ by sex, so check the label for your product.
From hypertension to hair: the unexpected story of minoxidil Minoxidil was developed as an oral blood-pressure drug and approved as Loniten in 1979; unwanted hair growth in patients led to topical Rogaine, approved for men in 1988 and for women in 1991. Trials support topical minoxidil for pattern hair loss, while low-dose oral minoxidil is a prescription drug used off-label and needs medical supervision.

learn Nanoxidil

learn Microneedling

Can microneedling make topical treatments like minoxidil work better? Microneedling can enhance the absorption and effectiveness of minoxidil.

learn Capixyl

Capixyl: Can it replace minoxidil or do they have to be used together? There is no published trial comparing Capixyl with minoxidil or testing the two together; the evidence for Capixyl is a manufacturer-run study of 30 people, while minoxidil is an approved treatment with decades of controlled trials behind it.

learn Hyaluronic Acid

Can hyaluronic acid help reduce scalp irritation from medical treatments like minoxidil? Yes, hyaluronic acid can help reduce scalp irritation from minoxidil.

learn Tretinoin

the gold standard retinoid in dermatology that's also helpful for hair regrowth alongside Minoxidil

learn Valproic acid

an anticonvulsant repurposed for hair loss via histone inhibition

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Community Join

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community Brotzu lotion update

87 upvotes 8 years ago

A new hair loss lotion by Dr. Brotzu, expected to regrow up to 5 years of lost hair, is set to be released by Fidia Farmaceutici. It claims to work like minoxidil and finasteride without side effects, but skepticism exists due to its classification as a cosmetic product.

community Minoxidil Skin Delivery from Nanoemulsion Formulations Containing Eucalyptol or Oleic Acid: Enhanced Diffusivity and Follicular Targeting

4 upvotes 1 year ago

Minoxidil can be effectively delivered through nanoemulsions containing eucalyptol or oleic acid, enhancing its diffusivity and targeting hair follicles. This contradicts the advice against mixing minoxidil with oils in topical formulations.

community Best minoxidil formulation for best results?

2 upvotes 1 year ago

The conversation discusses creating a customized minoxidil formulation with tretinoin, azelaic acid, and caffeine, but there are concerns about foam stabilization due to acidity. The user seeks advice on the best formulation for effective results.

community Topical minoxidil brand (and form of application) matters. You can be a hyper-responder to one product and a non-responder to another.

18 upvotes 1 year ago

Different minoxidil formulations affect hair growth and side effects. Higher propylene glycol and pH levels improve effectiveness but can cause scalp irritation.

community Minoxidil is a 5ar inhibitor according to research

150 upvotes 11 months ago

Minoxidil may inhibit androgen receptors and affect hormonal pathways, potentially explaining its effectiveness in treating androgenetic alopecia (AGA). Users discuss its varying effectiveness on scalp versus facial hair and note fewer side effects with topical use compared to oral.

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