1533 citations
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October 2008 in “Endocrine reviews”
Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
Oral minoxidil is gaining popularity due to increased awareness and convenience, despite potential side effects like cardiac issues and unwanted hair growth. Users report mixed results, with some seeing significant regrowth and others experiencing side effects or minimal improvement.
A user discussed using finasteride for six months to treat hair loss, noting minimal side effects and uncertain hair regrowth. They mentioned not using minoxidil and considering future options like hair transplants.
Veradermics' phase 2 trial of slow-release oral minoxidil shows promising hair regrowth with minimized side effects, gaining significant attention and funding. PP405 is also noted for its potential as a side-effect-free alternative.
Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.