6 citations
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November 2021 in “Journal of Ethnopharmacology” This review discusses the traditional uses, chemical components, and biological activities of Calanthe species, reporting no new findings; it underscores the need for conservation and further pharmacological research.
January 2026 in “Chemical Communications” This study found that calanthoside, a compound isolated from Calanthe species, promotes the proliferation of human hair follicle dermal papilla cells more effectively than minoxidil.
2 citations
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November 2023 in “Journal of Natural Products” In this study, researchers accomplished the total synthesis of calanthoside, noted for its strong proliferative effects on human hair follicle dermal papilla cells, using a seven-step process from anthranilic acid with a 43% overall yield.
January 2026 in “RSC Medicinal Chemistry” This study notes the ongoing challenge in developing new drugs for androgenetic alopecia, mentioning that both minoxidil and finasteride were originally intended for treating hypertension. Results are not reported.
3 citations
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April 2021 in “Chemical & Pharmaceutical Bulletin” This study found that indole glycosides from Calanthe discolor Lindl. can significantly promote the proliferation of human hair follicle dermal papilla cells, potentially through upregulating specific growth factors.