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Glossary C3H mice

specific lab mice strain used in cancer and genetics research

C3H mice are a specific strain of laboratory mice that are commonly used in scientific research. They are known for their susceptibility to developing certain types of cancers and for their use in studies related to immunology, genetics, and aging. This strain is also notable for its distinctive agouti coat color, which is a mix of brown and black fur.

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research Alopecia Areata in Aging C3H/HeJ Mice

178 citations , June 1994 in “Journal of Investigative Dermatology”

This study found that a non-scarring alopecia in C3H/HeJ mice resembles human alopecia areata and may serve as a valuable model for studying specific subtypes of the human condition.

research Experimental Induction of Alopecia Areata-Like Hair Loss in C3H/HeJ Mice Using Full-Thickness Skin Grafts

131 citations , November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study observed that alopecia areata can be induced and serially transferred in C3H/HeJ mice using skin grafts, providing a useful model for studying the disease in humans.

research Alopecia Areata in C3H/HeJ Mice Involves Leukocyte-mediated Root Sheath Disruption in Advance of Overt Hair Loss

37 citations , November 2003 in “Veterinary pathology”

This study showed that in C3H/HeJ mice, focal follicular inflammation starts before overt hair loss, with inflammation severity possibly reaching a threshold causing hair follicle dystrophy prior to visible hair loss.

research Effect of Leaves of Ginkgo biloba on Hair Regrowth in C3H Strain Mice

37 citations , January 1993 in “Yakugaku zasshi”

This study found that a 70% ethanolic extract from Ginkgo biloba leaves promotes hair regrowth in C3H mice.

research Murine Cytomegalovirus is Not Associated With Alopecia Areata in C3H/HeJ Mice

25 citations , June 1998 in “Journal of Investigative Dermatology”

Murine cytomegalovirus does not cause alopecia areata in these mice.

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