This study suggests that Crinum asiaticumvar. japonicum extract and its component norgalanthamine may promote hair growth by inhibiting 5α-reductase activity and the TGF-β1-induced pathway.
5 citations
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December 2018 in “Biological & Pharmaceutical Bulletin”
In this study, norgalanthamine was found to stimulate hair growth in cultured rat dermal papilla cells by activating the ERK 1/2, PI3K/AKT, and Wnt/β-catenin signaling pathways.
12 citations
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January 2010 in “European Journal of Dermatology”
In this study, an ethanol extract of Crinum asiaticum was observed to significantly increase hair-fiber lengths and promote hair growth in rat vibrissa follicles and C57BL/6 mice.
17 citations
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February 2015 in “Phytochemistry Reviews”
This review discusses the cosmetic potential of Southeast Asian herbs and highlights the need for more systematic scientific evaluation of their efficacy and safety.