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compound from cruciferous vegetables has some mild effects on DHT
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5 / 144 resultsresearch Sulforaphane-Rich Broccoli Sprout Extract Promotes Hair Regrowth in an Androgenetic Alopecia Mouse Model via Enhanced Dihydrotestosterone Metabolism
The study explores the effects of sulforaphane-rich broccoli sprout extract (BSE) on hair regrowth in a mouse model of androgenetic alopecia (AGA). BSE was found to enhance dihydrotestosterone (DHT) metabolism, a key factor in AGA, and promote hair regrowth by accelerating the telogen-to-anagen transition and increasing hair follicle length and weight. In vivo experiments showed that BSE, particularly at a 20 mg/kg dose, achieved hair regrowth comparable to finasteride and superior to minoxidil. BSE also reduced plasma testosterone and DHT levels, suggesting dual anti-androgenic effects, and activated the Wnt/β-catenin signaling pathway. The study highlights BSE's potential as a natural therapeutic agent for AGA, with improved safety and efficacy profiles compared to current treatments, although further clinical investigations are needed to evaluate its efficacy and safety in humans.
research Sulforaphane Mobilizes Cellular Defenses That Protect Skin Against Damage by UV Radiation
Sulforaphane from broccoli can help protect skin from sun damage.
research The Impact of Sulforaphane on Sex-Specific Conditions and Hormone Balance: A Comprehensive Review
Sulforaphane from broccoli may help treat certain cancers, hormone issues, and hair loss.
research Dietary Glucoraphanin Prevents the Onset of Psychosis in Adult Offspring After Maternal Immune Activation
Eating glucoraphanin can help prevent psychosis in offspring whose mothers had immune system activation.
research Oxidative Stress Management in the Hair Follicle: Could Targeting NRF2 Counter Age-Related Hair Disorders and Beyond?
Activating NRF2 might help treat hair disorders by improving antioxidant defenses.
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5 / 116 resultscommunity u/joaopassos4444 has zero education in endocrinology, human biology or science, it’s incredibly unlikely he good Will Hunting-ed a medical issue that stumped researchers for thousands of years, please stop buying random supplements based on layman speculation and temper your expectations
User questions credibility of a hair loss "cure" found by a non-expert and warns against wasting money on unproven supplements. Others discuss trying natural extracts and the importance of researching the enzyme 3ADH for potential hair growth benefits.
community 3 months on minoxidil and microneedling alone
This conversation was about a user's progress pictures from using minoxidil and microneedling to treat hair loss. Other users suggested finasteride as an additional treatment, while cautioning that the drug could have permanent side effects.
community Doing sulforaphane since 2 weeks got new babyhairs
The user noticed new baby hairs after using sulforaphane but is still experiencing shedding. They are seeking a supplement to stop shedding, possibly grape seed extract.
community What happened to the ‘funding’ for broccoli research in treating hair loss?
Hair loss discussion includes broccoli sprouts treatment, Fluridil 7%, and sulforaphane, with mixed results. Finasteride, minoxidil, and RU58841 are preferred by some users.
community As a follow up on u/joaopassos4444 's amazing post, short video of Sulforaphane supplements vs. broccoli sprouting. 2 brands are mentioned with the optimal dosage. Thought it would help!
The conversation discusses hair loss treatments, specifically Minoxidil, finasteride, RU58841, and Sulforaphane supplements. Two brands of Sulforaphane supplements, Avmacol and Prostaphane, are mentioned with optimal dosages.