22 citations,
January 2008 in “Physiological Research”
Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.
A user is using a Finoxidil topical spray and is curious if oral Finasteride would be more effective, considering they are already on a DHT blocker called Cyproterone. They are concerned about the potential impact of oral Finasteride on their transition.
Hair loss treatments like dutasteride, finasteride, minoxidil, and RU58841 are discussed, with mixed results and ongoing hope for better solutions. Users express skepticism about a cure, sharing experiences with various treatments and lifestyle changes.
SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.
Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.
The post and conversation are about the user's high testosterone levels and their worsening hair loss despite trying various treatments. They are considering using low doses of anti-androgens to lower their testosterone levels as a potential solution.