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Research

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research The Role of Box A ofHMGB1in Enhancing Stem Cell Properties of Human Mesenchymal Cells: A Novel Approach for the Pursuit of Anti-aging Therapy

1 citations , January 2023 in “In vivo/In Vivo”

This study suggests that the activation of box A in mesenchymal cell models may enhance stem cell properties, increasing the expression of stemness markers like OCT4, NANOG, and SOX2.

research Skin expression of mammalian target of rapamycin and forkhead box transcription factor O1, and serum insulin‐like growth factor‐1 in patients with acne vulgaris and their relationship with diet

93 citations , January 2016 in “British Journal of Dermatology”

This study found that patients with acne vulgaris had higher serum IGF-1 levels and more intense FoxO1 and mTOR expression than controls, suggesting their role in acne pathogenesis.

research OPTIMISATION OF AVICENNIA MARINA HEARTWOOD EXTRACT NANOEMULSION USING BOX–BEHNKEN DESIGN: FORMULATION CHARACTERISTICS AND ANTIFUNGAL EVALUATION

May 2026 in “International Journal of Applied Pharmaceutics”

This study developed a stable nanoemulsion of Avicennia marina heartwood extract showing promising anti-dandruff activity against Pityrosporum ovale and favorable physicochemical properties, which supports its potential use in topical formulations.

research BH19 ‘JAK in the box?’ Long-term safety concerns with oral Janus kinase inhibitors for alopecia areata

June 2025 in “British Journal of Dermatology”

This study reviewed clinical trials on JAK inhibitors for alopecia areata, finding them effective for short-term hair regrowth with a favorable safety profile, but noted limited data on long-term risks like malignancies or cardiovascular events beyond two years.

research Transnasal cooling: A Pandora’s box of transnasal patho-physiology

3 citations , May 2011 in “Medical Hypotheses”

This article proposes that transnasal evaporative cooling could advance understanding of various physiological phenomena, but reports no new clinical results; potential research directions are suggested for this concept.

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Community Join

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community Ordered Dutas, Almost got scammed but finally they sent it and that too in the original box

8 upvotes 2 months ago

The conversation is about a user ordering Dutas (dutasteride) from a website called emedicalwala, facing issues with the order and refund, and eventually receiving the product. The user advises against ordering from emedicalwala again despite finally receiving the softgels.

community If my pyrilutamide order from sets in my mail box for several hours will the temperature affect its efficacy?

in Product 11 months ago

The conversation discusses concerns about the efficacy of pyrilutamide if left in a mailbox for several hours. It also mentions treatments like Minoxidil, finasteride, and RU58841 for hair loss.

community Has anyone gone on a flight to Turkey, bought a backpack full of Avodart (say 12 months supply) and come back without Airport Security being a pain in the ass?

5 upvotes 2 weeks ago

A user is considering traveling to Turkey to buy a year's supply of Avodart cheaply and is concerned about airport security. Others suggest alternatives like buying from India or using powder form.

community New BBC article on Finasteride just dropped

in Chat 318 upvotes 1 year ago

Finasteride and minoxidil are discussed as hair loss treatments, with mixed opinions on side effects like sexual dysfunction and mood changes. Some users report positive results, while others express concerns about potential risks and insufficient information.

community Can anyone who’s Indian tell me, if this lonitab 2.5mg minoxidil by intas is real?

6 upvotes 1 week ago

The conversation confirms that Lonitab 2.5mg minoxidil by Intas is real and effective, with users reporting positive results. Some users suggest splitting the dose to avoid side effects, and others recommend considering reputable brands like Sun Pharmaceutical or Cipla.

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Experts

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SMP Specialist
Corey Box
Melbourne, VIC, Australia
1+ yrs

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Corey Box