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research Mitotic activity in the epidermis of the rabbit stimulated with local applications of testosterone propionate

25 citations , April 1949 in “The journal of experimental zoology”

This research studied the effect of local testosterone propionate applications on rabbit epidermal mitotic activity but reports no new results.

Metformin Promotes Mechanical Stretch-Induced Skin Regeneration by Improving the Proliferative Activity of Skin-Derived Stem Cells

research Metformin Promotes Mechanical Stretch-Induced Skin Regeneration by Improving the Proliferative Activity of Skin-Derived Stem Cells

1 citations , May 2022 in “Frontiers in medicine”

This study found that topical application of metformin significantly enhanced skin regeneration in mechanically stretched skin in rats, likely by boosting the proliferation of skin-derived stem cells.

research Testosterone alters iron metabolism and stimulates red blood cell production independently of dihydrotestosterone

53 citations , July 2014 in “American Journal of Physiology-Endocrinology and Metabolism”

This study found that testosterone-enanthate increased red blood cell production and altered iron homeostasis in older hypogonadal men without being affected by finasteride, indicating these effects do not require type II 5α-reductase enzyme activity.

research 4th Intercontinental Meeting of Hair Research Societies 2004 The "World of Hair"

1 citations , May 2004 in “Journal der Deutschen Dermatologischen Gesellschaft”

This article from the 4th Intercontinental Meeting of Hair Research Societies provides no abstract or new findings.

research UT-018 Accelerates Wound Repair and Hair Follicle Regeneration in Murine Models

1 citations , May 2026 in “bioRxiv (Cold Spring Harbor Laboratory)”

In laboratory studies on mice, Abstract UT-018, a stem cell chemoattractant formulation, was reported to significantly enhance wound healing and promote hair regeneration through mechanisms involving improved tissue formation, collagen organization, and follicular development.

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Community Join

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community Is this true? It can be a major breakthrough

1008 upvotes 4 months ago

Deoxyribose sugar gel may stimulate hair regrowth similarly to minoxidil by enhancing blood supply and follicle activity. Human trials are necessary, and current products have mixed results.

community Research: Minoxidil grows hair by suppressing androgen activity (DHT) in hair follicles.

43 upvotes 6 years ago

Minoxidil may suppress androgen activity in hair follicles, potentially aiding in hair growth and prostate cancer treatment. Users discuss the effectiveness of minoxidil and finasteride for hair maintenance and regrowth, with some preferring topical applications over oral due to safety concerns.

community Study: There is 70x Higher Unconjugated DHT in Feces Compared To Blood Levels in Young Adults - Gut Microbiota Manages DHT Recycling and Metabolism

in Research/Science 194 upvotes 1 year ago

Gut microbiota significantly influences androgen metabolism, impacting hair loss treatments like finasteride. Probiotics, dietary changes, and fecal microbiota transplants may help manage DHT levels and improve hair health.

community Tretinoin vs. micro-needling: what increases sulfotransferase activity more?

in Research/Science 1 upvotes 1 year ago

Tretinoin and microneedling both enhance hair growth through different mechanisms, with microneedling being considered safe for long-term use. Optimal microneedling needle length varies, but 0.8 mm is suggested for hair growth, and a Dermastamp is recommended to avoid skin damage.

community Rosemary oil's potency as a dht blocker

in Research/Science 65 upvotes 2 years ago

Rosemary extract showed high inhibitory activity against DHT, similar to finasteride and dutasteride, but the conversation includes skepticism about its effectiveness in humans since the study was done on mice and rosemary oil is often considered ineffective based on personal experiences. Some suggest trying rosemary oil alongside other treatments, while others emphasize the difference between the extract used in the study and the oil.

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Learn

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learn Stem Cell Factor

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Epidermal Growth Factor

learn Thymosin Beta 4

learn Vascular Endothelial Growth Factor

learn Centella

Ever wonder why your hair doesn’t grow back thick anymore? Maybe your scalp needs better blood flow: centella could help. There is no clinical trial of centella asiatica for hair loss and no study measuring scalp blood flow in people using it; the only hair-related evidence is a 2017 cell-culture study. Centella products are cosmetics that may soothe an irritated scalp, and the link between scalp circulation and pattern hair loss is itself unproven.

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Clinics

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