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Human Hair Follicles Can Taste: Stimulation of the Bitter Taste Receptor TAS2R4 Inhibits Hair Growth Ex Vivo by Up-Regulating TGF-β2

research 571 Human Hair Follicles can “Taste”: Stimulation of the Bitter Taste Receptor TAS2R4 Inhibits Hair Growth Ex Vivo by Up-Regulating TGF-β2

November 2022 in “Journal of Investigative Dermatology”

This study reports that activating the bitter taste receptor TAS2R4 with rebaudioside A can inhibit hair growth in human scalp hair follicles by promoting catagen through TGF-β pathway activation.

research Saliva secretion in engrafted mouse bioengineered salivary glands using taste stimulation

10 citations , January 2014 in “Journal of prosthodontic research”

This study found that while both natural and bioengineered salivary glands showed similar protein concentrations in response to taste stimulation, their protein compositions and amylase concentrations differed, which may affect nerve signal balance.

research A Comparison of Quality of Life and Nutritional Status after Gastrectomy in Korean Gastric Cancer Patient

April 2013 in “The FASEB journal”

This study found that improved nutritional status after gastric cancer surgery was associated with better quality of life, with malnourished patients experiencing greater eating restrictions, anxiety, and other issues.

research Aloe Vera Drink Fortification with Free and Microcapsulated Pumpkin Seed Protein Hydrolysate

1 citations , January 2024 in “Journal of Food Processing and Preservation”

This study found that adding microcapsulated pumpkin seed protein hydrolysate to aloe vera drinks improved antioxidant activity, taste, and shelf life, with chitosan-alginate microcapsules effectively inhibiting microbial growth during 30 days of refrigerated storage.

research Symptoms Compatible With Long Coronavirus Disease (COVID) in Healthcare Workers With and Without Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection—Results of a Prospective Multicenter Cohort

35 citations , January 2022 in “Clinical Infectious Diseases”

This study found that healthcare workers with a positive COVID-19 test reported long COVID symptoms more frequently than negative controls, while prior physical activity was linked to reduced neurocognitive and fatigue symptoms.

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Community Join

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community New topical Dutasteride from Moogene will have 20 times better scalp absorption than oral Dutasteride. And much lower system absorption.

in Finasteride/Dutasteride 178 upvotes 4 years ago

A new topical Dutasteride with 20 times better scalp absorption being developed and tested for release in 2023; use of existing drugs, such as Minoxidil and finasteride; and mesotherapy as an alternative hair loss treatment.

community [PSA] - Do NOT swallow dutasteride capsule content.

43 upvotes 9 months ago

Dutasteride capsules should not be bitten or opened due to their foul taste and potential caustic effects. Users shared experiences of accidentally biting capsules and the unpleasant taste, with some suggesting swallowing techniques to avoid this.

community Is RU58841 really a game changer ?

30 upvotes 4 years ago

Topical finasteride and minoxidil show some hair regrowth, but hair loss persists. RU58841 is considered effective by some users but is not well-tested, with potential side effects; it may be used alongside finasteride for better results.

community Hopefully this works better for hair than as a sweetener. I'm not getting my hopes up though. Everything seems to work on mice.

3 upvotes 11 months ago

A Stevia patch with Minoxidil showed positive results for hair growth in mice. A user experienced increased hair shedding after using finasteride for 12 months and briefly using minoxidil.

community 2023 study: Novel Hemp extract causes great hair (allegedly better than fin/min) growth with little to no side effects. Photos included… Thoughts?

8 upvotes 2 years ago

A novel hemp extract allegedly promotes better hair growth than minoxidil and finasteride, with minimal side effects, but the study's credibility is questioned due to potential bias and confounding factors like peppermint oil. Users express skepticism and suggest sticking with proven treatments like minoxidil and finasteride.

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Learn

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learn Peppermint

Is it better to use peppermint alone or in combination with rosemary or lavender? No study has tested peppermint with rosemary or lavender in combination, in people or in animals, so the synergy claim is a hypothesis. Of the three, only rosemary oil has a published human trial — 100 patients over six months, where it matched 2% minoxidil on hair count — while peppermint and lavender have four-week mouse studies only.

learn Overview

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Hair Transplant

Does a higher graft count always lead to better results in a hair transplant? Better results depend on graft quality and placement, not just higher graft counts.

learn shea butter

learn cupuacu butter

learn Ketoconazole

Ketoconazole: Does it work better if I leave it on my scalp longer? Leaving ketoconazole on your scalp longer may enhance its effectiveness.
Is it better to buy a ketoconazole shampoo from a pharmacy or a brand name one? Approved generic and brand-name ketoconazole shampoos carry the same active ingredient at the same strength, and regulators require a generic to be shown equivalent to the product it copies; no published head-to-head trial compares them, and generics are usually the cheaper option.

learn GHK-Cu

GHK-Cu: Is it better than minoxidil or finasteride, or just a complement? There is no completed human trial of GHK-Cu for androgenetic alopecia, so it cannot be compared with minoxidil or finasteride on evidence; clinics and community users treat it as an unproven add-on, not a replacement.

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Clinics

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32
Hair Loss Treatments
A Taste of T SalonAugusta, GA · US

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