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research Biological Skin Rejuvenation in the Regenerative Era: Clinical Applications of Exosomes and Polynucleotides in Modern Dermatology

July 2026 in “International Science Journal”

This review discusses current findings in regenerative dermatology, noting promising results for therapies using exosomes and polynucleotides in skin rejuvenation and healing, while highlighting the need for more standardized protocols and long-term studies to confirm their effectiveness and safety.

research Peripheral Skin Temperature and Circadian Biological Clock in Shift Nurses after a Day off

49 citations , April 2016 in “International journal of molecular sciences”

This study found that shift nurses exhibited lower circadian variations compared to daytime nurses, indicating an adjustment of their biological clocks to continuous shift schedules.

research Biological activities supporting development of cosmeceutical skin products from Wedelia trilobata (L.) Hitch. flower extract

3 citations , January 2023 in “Agriculture and Natural Resources”

This study found that flower extracts of Wedelia trilobata may serve as a promising active ingredient for cosmeceutical products due to their antioxidant, anti-inflammatory, and antimicrobial properties.

research 1372 Biological effects of electrical epilation on human hair follicles and perifollicular skin ex vivo

April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study found that electrical epilation in organ-cultured human scalp skin perturbs hair follicles by causing inflammation, impairing melanin production, and possibly inhibiting post-epilation hair re-growth.

research Revealing biological mechanisms of skin pigment recovery during treatment in vitiligo patients: A proteomic analysis

June 2026 in “Journal of Investigative Dermatology”

This study found that certain proteins linked to immune suppression and melanogenesis are associated with repigmentation in vitiligo patients undergoing standard treatment, suggesting these proteins and their pathways play roles distinct from merely reversing skin lesions.

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Community Join

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community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

63 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community Adding Creatine while on fin + min has caused my skin to become red and terrible

3 years ago

Adding creatine while using finasteride and minoxidil caused skin irritation and hair thinning. Creatine may affect DHT levels, leading to these issues.

community Why hasn’t anyone made a "DHT sponge" biologic yet???

in Research/Science 45 upvotes 10 months ago

The conversation discusses the potential for developing a biologic "DHT sponge" to neutralize DHT in the bloodstream as a treatment for hair loss, suggesting it could be more targeted and have fewer side effects than current treatments like finasteride and dutasteride. Concerns include the complexity, cost, and potential side effects of such a treatment, as well as skepticism about its feasibility and market interest.

community Minoxidil actually reduces wrinkles

in Research/Science 209 upvotes 1 year ago

Minoxidil may improve or worsen skin quality, with topical forms causing dryness and wrinkles, possibly due to alcohol content, while oral forms have fewer side effects. Some users consider using tretinoin to mitigate negative effects.

community Does finasteride/dutasteride reverse aging?

in Chat 45 upvotes 1 year ago

Finasteride and dutasteride can improve skin texture and reduce acne by lowering DHT but do not reverse aging. They may enhance skin and hair health for some, but can also cause side effects like dry skin and sexual dysfunction.

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Learn

6 / 801 results

learn Follistatin

glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

learn Epidermal Growth Factor

learn GHK-Cu

a copper peptide showing promise in both regrowth and reversing gray hair

learn Thymosin Beta 4

learn sh-Polypeptide-7

learn Valproic acid

What biological mechanisms related to hair follicles are linked to valproic acid in experimental treatments? Valproic acid affects hair follicles by modulating cell signaling and gene regulation.

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Clinics

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Trichology
Real Trans Hair Biological Rejuvenation ClinicMoscow · RU

Experts

2 / 195 results