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      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

      learn Alfatradiol

      a synthetic estrogen used topically as an anti-androgen

      learn GHK-Cu

      a copper peptide showing promise in both regrowth and reversing gray hair

      learn Exosomes

      Microscopic delivery system that sends growth-promoting signals to hair follicles

      learn Follistatin

      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

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      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 11 months ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

      community Guys, we finally have an alternative to finasteride

      in Research/Science  261 upvotes 2 months ago
      A combination of pyrilutamide, minoxidil, and alfatradiol is proposed as an effective alternative to finasteride for treating mild to moderate hair loss, claiming to stabilize hair loss and improve thickness without finasteride's side effects. Some users are skeptical about the effectiveness and approval of these treatments, while others are interested in trying them due to finasteride's side effects.

      community Why do we get bald from evolutionary perspective

      in Chat  213 upvotes 1 month ago
      Baldness is not an evolutionary disadvantage because it occurs after reproductive age. Treatments like Minoxidil and Finasteride are used for androgenetic alopecia but don't address the root cause.