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Glossary Becker's nevus

benign skin condition with a dark, hairy patch

Becker's nevus, also known as Becker melanosis, is a benign skin condition characterized by a large, irregularly shaped, hyperpigmented patch, often appearing on the upper trunk or shoulder. This patch may become more noticeable during adolescence and can be accompanied by an increase in hair growth (hypertrichosis) within the affected area.

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research Becker’s Nevus Syndrome in a Pediatric Female Patient

7 citations , January 2016 in “Case reports in pediatrics”

This study reports that antiandrogen medication, specifically 50 mg/day of spironolactone, showed an adequate clinical response in treating breast hypoplasia associated with Becker's nevus syndrome.

research Becker nevus of the face with asymmetrical growth of beard hair

February 2013 in “Journal of the American Academy of Dermatology”

This study found that certain polymorphisms in EGF and EGFR genes may increase susceptibility to alopecia areata in the Korean population, and these genetic variations could be associated with specific symptoms such as nail involvement and body hair loss.

research PA15 Becker naevus syndrome associated with a mosaic pathogenic variant in ACTB

June 2023 in “British journal of dermatology/British journal of dermatology, Supplement”

This case report describes a 15-year-old girl with features of Becker naevus syndrome, highlighting the importance of DNA analysis from skin to confirm the diagnosis after 9 years of symptoms.

research Postzygotic Mutations in Beta-Actin Are Associated with Becker’s Nevus and Becker’s Nevus Syndrome

62 citations , March 2017 in “Journal of Investigative Dermatology”

Mutations in the ACTB gene cause Becker’s nevi and may lead to muscle issues in Becker’s nevus syndrome.

research Becker's Nevus with Ipsilateral Breast Hypoplasia: Improvement with Spironolactone

29 citations , February 2003 in “Journal of Dermatology”

This case report describes a woman with Becker's nevus and ipsilateral breast hypoplasia who showed breast enlargement after one month of spironolactone treatment, suggesting a link between hypoplasia and increased androgenic receptor activity.

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