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This study found that basal lower proximal cup cells in mice are key to regenerating hair follicles after chemotherapy-induced damage, while traditional bulge stem cells remain inactive.

In this study, the researchers observed that post-radiation hair follicle repair in 3D architecture occurs through independent, long-range cell movements along the basal surface, resembling 2D healing processes.

This study suggests that damaged anagen hair follicles have the capability to repair themselves and resume growth by mobilizing extra-bulge epithelial cells, particularly after injuries like chemotherapy and radiotherapy.

This study observed that human hair follicles with a completely destroyed bulb can regenerate after being grafted onto immunodeficient mice, entering a shortened dystrophic telogen followed by anagen phase.

In this study, CD4+ non-haematopoietic, skin-resident stem cell-like populations were identified in both murine and human epidermis, suggesting they may serve as potential basal cell carcinoma precursors.