learn Follistatin
glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin
Search
forLearn
5 / 8 resultslearn sh-Polypeptide-7
learn Thymosin Beta 4
learn Epidermal Growth Factor
learn Overview
Research
5 / 1000+ resultsresearch Trichohyalin Mechanically Strengthens the Hair Follicle
Trichohyalin makes hair follicles stronger.
research Camellia Sinensis Seed Flavonoids Attenuate UVB-Induced Inflammation and UVA-Induced Photodamage via MAPK/NF-κB and AP-1 Pathways
This study investigated the effects of Camellia sinensis seed flavonoids (CSF) on UVB-induced inflammation and UVA-induced photodamage in human skin cells. CSF was found to significantly reduce reactive oxygen species (ROS) and inflammatory factors by inhibiting the p38/JNK and NF-κB pathways, as well as iNOS and COX-2 expression. In keratinocytes, CSF downregulated Caspase-3 and upregulated barrier proteins, while in fibroblasts, it enhanced collagen and hyaluronic acid production by modulating the AP-1 and TGF-β/Smad pathways. These findings suggest that CSF has potential as a skincare ingredient due to its anti-inflammatory, barrier-repair, and anti-photoaging properties.
research Mutations In AEC Syndrome Skin Reveal A Role For p63 In Basement Membrane Adhesion, Skin Barrier Integrity And Hair Follicle Biology
Mutations in the p63 gene affect skin adhesion, barrier integrity, and hair growth.
research Exosomes Derived from Adipose Tissue-Derived Mesenchymal Stem Cells for the Treatment of Dupilumab-Related Facial Redness in Patients with Atopic Dermatitis
Adipose stem cell exosomes can effectively reduce facial redness and improve skin health in atopic dermatitis patients.
research Hair Follicles Are Critical Modulators of Skin Barrier Function
Hair follicles are crucial for maintaining skin barrier function.
Community Join
5 / 251 resultscommunity Lion Mane Part 2: Microneedling with Topicals, beneficial compounds, maybe?
The conversation discusses microneedling techniques and the use of Minoxidil, copper peptides, EGF, FGF, ceramides, and hydration serums to enhance hair growth. It explores optimizing scalp conditions and the potential benefits of various compounds in conjunction with microneedling.
community DHT and 5AR respect post, it's importance within the brain
The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.
community Minoxidil alternative with a week long half-life? Why isn’t it possible?
This conversation discussed the potential for a hair loss treatment alternative to minoxidil, with many users debating the economic and health implications of such an option. Some suggested that finasteride could be used as an alternative, while others argued that this would ultimately not benefit pharmaceutical companies due to their reliance on planned obsolescence.
community Why hasn’t anyone made a "DHT sponge" biologic yet???
The conversation discusses the potential for developing a biologic "DHT sponge" to neutralize DHT in the bloodstream as a treatment for hair loss, suggesting it could be more targeted and have fewer side effects than current treatments like finasteride and dutasteride. Concerns include the complexity, cost, and potential side effects of such a treatment, as well as skepticism about its feasibility and market interest.
community IGF-1 and Peptides? Miracle molecule waiting to be found
The conversation discusses potential hair loss treatments focusing on stimulating IGF-1 at the follicle level using growth-factor cocktails and engineered peptides, such as Acetyl Tetrapeptide-3, Copper Tripeptide-1, Oligopeptide-20, Thymosin-β4, and Palmitoyl Tetrapeptide-7. It suggests that device-assisted delivery methods like microneedling may enhance effectiveness.