April 2019 in “Institutional Repositories DataBase (IRDB)” This study demonstrated that human iPSC-derived melanocytes, when transplanted into mice, can reconstitute pigmented hair follicles and integrate into normal tissue, suggesting their potential as a cellular therapy for depigmentation.
31 citations
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April 2019 in “Cell reports” This study found that human iPSC-derived melanocytes from vitiligo patients successfully integrated into mouse hair follicles and epidermis, demonstrating potential for personalized therapy for depigmentation.
May 2026 in “International Journal of Molecular Sciences” This study found that plucked hair follicles can serve as a practical and scalable source for regenerative medicine, as researchers successfully isolated and expanded keratinocytes and mesenchymal stem cells for potential cell-based and cell-free therapies, demonstrating significant wound-healing bioactivity in vitro.
5 citations
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November 2021 in “Plastic and Reconstructive Surgery” This article reviews the potential of using induced pluripotent stem cells for hair restoration, underscoring their promise over current surgical methods, but reports no new clinical results.
June 2022 in “Genetic engineering & biotechnology news” This article presents Stemson Therapeutics' development of a stem cell-based approach to generate new hair follicles for treating hair loss, which remains in preclinical stages without tested human results.