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      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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      natural substance from Neem tree with medicinal and pesticidal properties

      learn Tofacitinib

      a JAK inhibitor for alopecia areata and other autoimmune conditions

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      community Autoimmune issue?

      in Question  2 upvotes 7 years ago
      The user experienced severe hair loss, itchy scalp, and skin issues after trying no-shampoo, and wonders if it's male pattern baldness or an immune issue. They have a history of eczema, dermatitis, and jock itch, and have tried various treatments like coconut oil, peppermint, pumpkin seed, and onion.

      community The Worst Hair Loss Condition You (MAY) have: LPP

      in Research/Science  43 upvotes 9 months ago
      Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

      community Attacking DHT synergistically both locally at the scalp and systemically = Greater Success??

      in Finasteride/Dutasteride  13 upvotes 4 weeks ago
      The user has been using oral Dutasteride, RU58841, and Minoxidil for three years without success and is considering adding topical Finasteride or Dutasteride to target DHT both locally and systemically. Other users suggest sticking to a consistent treatment plan, exploring different combinations, and considering other factors like potential misdiagnosis or inconsistent medication use.