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research Autoimmune disorders associated with type 1 diabetes: clinical overview and principles of management

December 2023 in “Paediatrics & Family Medicine/Pediatria & Medycyna Rodzinna”

This article summarizes research on the co-occurrence of autoimmune diseases in patients with type 1 diabetes, noting that such conditions, present in up to 29% of these patients, can adversely impact their quality of life and diabetes management.

research Alopecia Areata Developing in Non-Insulin Dependent Diabetes Mellitus Type-2, an Autoimmune Disease

January 2019 in “Current research in diabetes & obesity journal”

A woman with type 2 diabetes developed alopecia areata, suggesting a link between the two autoimmune conditions.

research Type 1 Diabetes Mellitus and Autoimmune Diseases: A Critical Review of the Association and the Application of Personalized Medicine

12 citations , February 2023 in “Journal of Personalized Medicine”

This review discusses the complex interplay of genetic and environmental factors in Type 1 Diabetes Mellitus and its frequent association with other autoimmune conditions, focusing on personalized medicine to potentially improve patient care.

research Associations between type 1 diabetes and autoimmune skin diseases: Mendelian randomization analysis

4 citations , June 2024 in “Heliyon”

This study found a causal relationship between type 1 diabetes and autoimmune disorders such as SLE, RA, and MS in Europe, but not between T1DM and SLE in East Asia, highlighting the need for preventive monitoring in affected regions.

research Peripherally-Derived Regulatory T Cells in Mouse Autoimmune Diabetes

January 2019 in “eScholarship (California Digital Library)”

This study concluded that CNS1-dependent peripheral Tregs do not significantly impact type 1 diabetes in the NOD mouse model, with thymus-derived Tregs being the primary regulators.

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Community Join

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community Dear Dut users,have you noticed any metabolic changes with use of the drug?

6 upvotes 1 year ago

Dutasteride users have mixed results in hair loss treatment, with some experiencing improvements and others worsening. Some report metabolic changes like weight gain or diabetes, while others have no significant side effects.

community Anyone here have a lot of knowledge on hair follicle stem cells and progenitor cells for PP405?

in Chat 4 upvotes 8 months ago

Hair follicle stem cells remain in bald individuals, but progenitor cells do not, raising questions about hair regrowth claims by Pelage. PP405 is discussed as a potential treatment, with skepticism about its effectiveness compared to existing treatments like Minoxidil and Finasteride.

community Why is my dermatologist strictly against derma stamping/derma rolling?

in Microneedling 27 upvotes 1 year ago

Dermatologists often advise against at-home microneedling due to risks of scarring, infection, and improper technique. Professional guidance is recommended for safe and effective use, with some users reporting positive results when done correctly.

community Dutasteride Isn't Working? Get a Scalp Biopsy NOW

in Finasteride/Dutasteride 19 upvotes 1 year ago

Dutasteride may not be effective for everyone due to underlying issues, suggesting scalp biopsies for further diagnosis. Users discuss using higher doses of dutasteride, topical treatments, minoxidil, and pyrilutamide for hair loss management.

community CRISPR Is Curing People Right Now. Genetic Hair Loss is Next?

112 upvotes 1 year ago

CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.

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Learn

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learn Metformin

diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

learn Overview

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Cetirizine

Could cetirizine help control autoimmune triggers in alopecia areata? No published trial has tested cetirizine in alopecia areata; one registered trial has not reported results. Small trials in pattern hair loss report modest benefit, so any use for alopecia areata is off-label and unproven.

learn Tofacitinib

What is tofacitinib, and why is it discussed in relation to autoimmune-related hair loss such as alopecia areata? Tofacitinib is a prescription JAK inhibitor approved for rheumatoid arthritis, psoriatic arthritis and ulcerative colitis — not for alopecia areata. It is discussed for hair loss because a 2014 case report and a 2016 open-label trial reported regrowth in severe alopecia areata, but that use is off-label, the regrowth relapsed after stopping, and the drug carries an FDA boxed warning.

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Clinics

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13
Hair Loss Treatments
DECON (Diabetes & Endocrine Center of Nevada) SparksSparks, NV · US

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