research The role of mutations on gene AR, in androgenetic alopecia syndrome
This article reviews the pattern and progression of androgenic alopecia in men and women, but it does not present new clinical findings.
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research Identification of two additional novel mutations in the AR gene associated with severe forms of androgen insensitivity syndrome
In this study, genetic testing confirmed the diagnosis of Androgen insensitivity syndrome in most CAIS patients in Tunisia and identified two previously unreported mutations in the androgen receptor gene.
research A Novel Androgen Receptor Gene Mutation in a 46,XY Patient: Complete Androgen Insensitivity Syndrome
This case report identifies a novel AR gene mutation in an adolescent with primary amenorrhea, suggesting that CAIS should be considered when evaluating patients with a female phenotype and breast development.
research Sequence of the intron/exon junctions of the coding region of the human androgen receptor gene and identification of a point mutation in a family with complete androgen insensitivity.
This study identified a mutation in the steroid-binding domain of the androgen receptor gene associated with complete androgen insensitivity syndrome, impairing male sexual development due to altered androgen receptor protein function.
research A Mouse Model for the Basal Transcription/DNA Repair Syndrome Trichothiodystrophy
This study found that mimicking the XPD point mutation in mice resulted in trichothiodystrophy-like symptoms, supporting the role of basal transcription and DNA repair defects in the disease.
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5 / 448 resultscommunity So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)
There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.
community Been on Dut since 2022, new doctor has concerns.
A 31-year-old man has been using Dutasteride since 2022, alongside topical Minoxidil, with positive results and no issues. His new healthcare provider expressed concerns about long-term Dutasteride use and suggested alternatives like oral Minoxidil and Spironolactone, but the patient is hesitant to change a successful routine.
community The Real Cause Of Androgenetic Alopecia
Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.
community We already know how to permanently fix hair loss. The science is done. The only thing missing is the funding to run one experiment.
A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.
community Everything you ever wanted to know about Pelage Pharma's PP405: how it works and what to expect
PP405 may encourage earlier hair growth and slightly increase visible hair count but does not reverse hair follicle miniaturization in male pattern baldness. It does not address damage to the dermal papilla or broken Wnt signaling.
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DermatologistIara Carneiro, MD
Campinas, SP, Brazil
- 82
Hair Transplant SurgeonDr. Yawar Sajjad, MBBS, FCPS
Lahore, Pakistan
- 18
Hair Transplant SurgeonDr. Karishma Awari
Pune, Maharashtra, India
- 77
Hair Loss SpecialistKarley Weir
Preston, England, United Kingdom
- 82
DermatologistDr. Zachary W. Eyre, MD, MBA, FAAD
Atlanta, GA, United States
Clinics
3 / 13 results- 75Hair TransplantTrichologyDermatologyClinica Vanessa Mutton - Transplante Capilar e DermatologiaSorocaba, SP · BR
- 37TrichologyHair Loss TreatmentsSpecjalista Trychologii Medycznej Katarzyna Czarnacka Medical Beauty And SkinKraśnik · PL
- 26TrichologyAnalizy Medyczne Warszawa, Podolog WarszawaUrsynów · PL
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