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The Effects of Metformin, Ethinyl Estradiol/Cyproterone Acetate, and Their Combination Therapy on Carotid Artery Intima-Media Thickness in Patients with Polycystic Ovary Syndrome

research The Effects of Metformin, Ethinyl Estradiol/Cyproterone Acetate, and Their Combination Therapy on Carotid Artery Intima-Media Thickness in Patients with Polycystic Ovary Syndrome

February 2020 in “İstanbul medical journal”

Metformin improves early signs of heart disease in women with PCOS and raises apelin levels, but doesn't significantly change artery thickness.

research Evaluation of Serum Apelin-13 in Psoriasis Vulgaris Patients

January 2020 in “Benha Journal of Applied Sciences”

People with psoriasis have higher levels of Apelin-13 in their blood than healthy people.

research Serum Level of Apelin-12 in Acne Patients: Is It a Marker of Disease Severity?

April 2025

Higher apelin-12 levels may indicate more severe acne.

research Expression of Three Adipokines (Adiponectin, Leptin, and Resistin) in Normal Canine Skin: A Pilot Study

4 citations , November 2018 in “Journal of comparative pathology”

The three adipokines—leptin, adiponectin, and resistin—are present in various cells of normal dog skin.

research Metformin Effects on Blood Levels of Gremlin-1 in Polycystic Ovarian Women

April 2023 in “PubMed”

Metformin lowers gremlin-1 and improves insulin resistance in women with PCOS.

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Community Join

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community Age-linked hair loss caused by disappearing collagen, researchers say

61 upvotes 6 years ago

Age-linked hair loss is linked to disappearing collagen. Treatments discussed include minoxidil, finasteride, RU58841, tretinoin, microneedling, and collagen supplements.

community Can i Just buy any Melatonin Spray and use it in my head?

in Product 16 upvotes 2 years ago

The post is about a user considering using topical Melatonin for hair loss and asking if any melatonin spray can be used for this purpose. The user also seeks clarification on the required percentage of Melatonin in the spray, while a respondent shares their experience of the spray making them sleepy.

community 80 days finasteride + minoxidil + microneedling. Crazy density increase

in Progress Pictures 485 upvotes 7 months ago

A user experienced significant hair density increase after 80 days using oral finasteride, topical minoxidil, and microneedling with a derma pen. They reported minimal side effects and attributed their success to being a hyper responder to the treatments.

community Melatonin a possible tool to help fight AGA hair loss.

in Research/Science 50 upvotes 4 years ago

Topical melatonin may help reduce hair loss and increase hair thickness in people with androgenetic alopecia (AGA), with some studies showing positive results. It can be mixed with minoxidil for application, and its effectiveness might be enhanced when used with micro-needling, but results may vary among individuals.

community "DHT Itch" and onset Seborrheic Dermatitis

in Research/Science 76 upvotes 2 years ago

The post and conversation discuss the link between DHT (a hormone), scalp itchiness, and hair loss. Some users share their experiences and treatments, including the use of fluconazole, corticosteroids, and ketoconazole shampoo, with one user suspecting minoxidil as a potential cause of their symptoms.