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research The impact of anxiety level on the outcome of alopecia therapy in women

2 citations , July 2025 in “Consilium Medicum”

This study found that in women with alopecia, anxiety levels significantly decreased with temgikoluril alongside standard therapy over 12 weeks, enhancing emotional well-being and treatment satisfaction compared to the control group receiving only standard therapy.

research PSICODERMATOSES E A PREVALÊNCIA DE ANSIEDADE: REVISÃO DE LITERATURA

August 2023 in “Revista Ibero-Americana de Humanidades, Ciências e Educação”

This systematic review found that anxiety disorders are significantly more prevalent among patients with various psychodermatoses compared to the general population.

research Therapeutic potential of extracellular vesicles derived from Platycladus Orientalis leaf in treating anxiety, depression, and insomnia

September 2025 in “Frontiers in Pharmacology”

This study suggests that P. orientalis leaf-derived EVs could offer anxiolytic, antidepressant, and sleep-inducing benefits by affecting neurotransmitter levels and reducing inflammation, particularly when administered intranasally.

research In Quest of the Mysterious Holistic Vedic Herb Bacopa monnieri (L.) Pennell

1 citations , June 2023 in “Pharmacognosy Research”

This review highlights the promising therapeutic potential of Bacopa monnieri in treating various health conditions, particularly related to neuropharmacology, but emphasizes the need for further clinical research.

research Chronic progesterone treatment augments while dehydroepiandrosterone sulphate prevents tolerance to ethanol anxiolysis and withdrawal anxiety in rats

27 citations , April 2007 in “European Journal of Pharmacology”

Progesterone increases alcohol tolerance and withdrawal anxiety, while DHEAS prevents them.

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community Androsterone as a Neurosteroid Replacement Strategy for 5α-Reductase Inhibitor–Associated Sexual and Affective Dysfunction

in Research/Science 36 upvotes 2 months ago

Androsterone may help with sexual and affective dysfunction from finasteride by replacing disrupted neurosteroids without increasing androgenic side effects. Controlled testing is needed to confirm its effectiveness and safety.

community Finasteride does deplete important nuero-active steroids

11 upvotes 3 years ago

Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.

community PSA: Most men who stay on Fin will see the sexual side effects go away. Stop the fear mongering

192 upvotes 4 years ago

Finasteride can cause sexual side effects in less than 2% of men, but these often disappear over time, even if the treatment continues. Some users report persistent side effects, while others experience no issues or only temporary ones.

community 18M 8 months progress 40mg daily dut stack

in Progress Pictures 112 upvotes 1 year ago

An 18-year-old is using a high-dose hair loss treatment with 40mg daily dutasteride, finasteride, minoxidil, tretinoin, and topical bicalutamide. Despite health risk concerns, especially liver issues, they report hair regrowth progress and intend to continue the regimen.

community 5 alpha reductase type 1 is in brain tissue producing the main endogenous gabaergic allopregnanolone, not 2. How can finasteride as a 5ar2 lower that?

27 upvotes 1 year ago

Finasteride and dutasteride are discussed for hair loss, with concerns about their effects on neurosteroids and potential side effects like depression. Alternatives like topical estrogen and lifestyle changes are considered, with varying opinions on mental health and hair regrowth.

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