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research T-Cell Induced-Self MHC Class I/Peptide Complexes May Enable De Novo Tolerance Induction to Neo-Antigens Occurring Outside of the Thymus
Hair follicles may help teach the immune system to tolerate new self-antigens, but this can sometimes cause hair loss.
research Characterization of Hair Follicle Antigens Targeted by the Anti-Hair Follicle Immune Response
research Distribution of Major Histocompatibility Antigens in Normal Skin
Major histocompatibility antigens are found in specific skin cells and structures, but not in sweat glands.
research The Sex-Linked Histocompatibility Antigens
Male-to-female skin grafts in mice are rejected due to sex-linked antigens.
research Transduction-Induced Overexpression of Merkel Cell T Antigens in Human Hair Follicles Induces Formation of Pathological Cell Clusters with Merkel Cell Carcinoma-Like Phenotype
Overexpressing Merkel cell virus proteins in human hair follicles can create clusters of cells that resemble Merkel cell cancer.
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5 / 21 resultscommunity 25F and have been losing my hair for 10 years. Been to doctors, no issues with thyroid or hormones. No history of hair loss in my family. Wtf do I do?
A 25-year-old woman has been losing hair for 10 years despite normal thyroid, hormone levels, and B12 supplementation. She has used Minoxidil with limited success and is considering hair transplants, Propecia, or shaving her head and wearing wigs.
community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied
Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
community Physician here AMA – 30M oral Fin 1-1.25 mg daily
Hair loss treatments, specifically the use of finasteride, microneedling and potentially oral minoxidil. People discussed their experiences with finasteride, its effects on sexual behaviors, as well as potential solutions such as tadalafil or using other growth factor signal peptides for hope in curing male pattern baldness.
community 28M Starting Finasteride for Accelerating Hair Loss – Seeking Monitoring Advice
The user plans to start a 12-month finasteride treatment to combat aggressive hair loss, with regular monitoring of thyroid levels, testosterone, DHT, liver enzymes, PSA, and iron levels. They seek advice on additional monitoring and aim to balance results with minimal side effects.
community Interpreting pre-finisteride blood panels
The conversation is about someone planning to start finasteride for hair loss and wanting to interpret pre-treatment blood panels to assess the risk of side effects like gynecomastia. They list various tests to measure hormone levels and other health indicators.