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research Acquired immunogenicity of DNA after modification with malondialdehyde in patients with alopecia areata

10 citations , March 2014 in “Scandinavian journal of clinical and laboratory investigation”

This study found that MDA-modified DNA may contribute to immune responses in alopecia areata patients by creating neo-epitopes, providing new insights into the condition's immunological mechanisms.

research Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model

48 citations , September 2020 in “Frontiers in Immunology”

In this study, researchers found that loss of OGG1 in a mouse model of systemic lupus erythematosus increased IFN-driven immune responses and aggravated skin lesions, suggesting a protective role for OGG1 in SLE skin disease.

research Systemic Lupus Erythematosus

37 citations , January 1979 in “Archives of Dermatology”

This case report suggests that PUVA treatment may have played a role in triggering systemic lupus erythematosus in a 23-year-old woman with psoriasis.

research Systemic Lupus Erythematosus—Vasculopathy/Vasculitis, Susac Syndrome, and Myasthenia Gravis

December 2010 in “Elsevier eBooks”

This article discusses the clinical manifestations of systemic lupus erythematosus and their potential mechanisms, but reports no new experimental results.

research A case of simultaneous onset of highly active systemic lupus erythematosus and IgG4-related renal disease

3 citations , January 2022 in “Modern Rheumatology Case Reports”

This case report details a rare instance of simultaneous onset of systemic lupus erythematosus and IgG4-related disease in a 73-year-old woman, where treatment improved symptoms by using high-dose glucocorticoids, hydroxychloroquine, and belimumab.

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community Androgen degraders for hair loss

61 upvotes 2 years ago

The conversation discusses androgen receptor degraders for hair loss, highlighting their potential advantages over traditional AR blockers like RU58841 and pyrilutamide. Concerns about the safety and cost of these treatments are also mentioned.

community Losing a ton consistently after 8 months dut please help me I don’t know what to do anymore, nothing works

in Chat 76 upvotes 1 year ago

A 20-year-old is experiencing hair loss despite using dutasteride and oral minoxidil. Suggestions include consulting a specialist, considering RU58841, and checking for other conditions and vitamin deficiencies.

community How is this even possible that there is no cure till now

in Technology 155 upvotes 4 months ago

There is no permanent cure for hair loss; treatments like finasteride, minoxidil, and hair transplants require ongoing use and are not universally effective. Genetic complexity and financial incentives for ongoing treatments hinder the development of a definitive cure.

community Genomic Sequencing for Hair Loss

in Research/Science 156 upvotes 5 months ago

Hair loss treatments like Minoxidil, finasteride, and potential mRNA therapies are discussed. There is skepticism about targeting specific genes due to the complex genetic nature of hair loss.

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