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Psoriatic Alopecia/Alopecia Areata–Like Reactions Secondary to Anti–Tumor Necrosis Factor-α Therapy: A Novel Cause of Noncicatricial Alopecia

research Psoriatic Alopecia/Alopecia Areata–Like Reactions Secondary to Anti–Tumor Necrosis Factor-α Therapy: A Novel Cause of Noncicatricial Alopecia

72 citations , February 2011 in “The American Journal of Dermatopathology”

This study found that anti-TNF therapy-induced alopecia exhibits distinct clinical and histopathological features and can mimic psoriatic alopecia and alopecia areata, with some patients improving with topical treatment.

research New potential antiscarring approaches

10 citations , July 2011 in “Wound Repair and Regeneration”

This article proposes several potential approaches for scar prevention and therapy, including anti-transforming growth factor-β strategies and tissue-engineered skin, but reports no new clinical results.

research Pathological Skin Scarring: From Mechanism to Targeted Local Therapy

June 2026 in “Preprints.org”

This review examines the mechanisms behind pathological scarring like hypertrophic scars and keloids, highlights the limitations of current treatments, and suggests that biomaterial-enabled delivery of anti-fibrotic statins, such as atorvastatin, may offer a promising therapeutic avenue for managing these scars.

Wound Healing, Cutaneous Therapy, and Hair Growth

research 14. Wound Healing; Cutaneous Therapy; Hair

February 2008 in “Medical & surgical dermatology”

Some treatments like topical oxygen and stem cells show promise for wound healing and hair growth, but evidence for modern dressings over traditional ones is limited.

research Aging and Anti-Aging in Hair and Hair Loss

1 citations , September 2013 in “Elsevier eBooks”

This review discusses factors affecting hair aging, such as inflammation and UV exposure, and examines potential anti-aging benefits of antioxidants and nutraceuticals for hair, but reports no new clinical results.

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community Quote from Pelage (PP-405) Spokesperson...

122 upvotes 11 months ago

Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

community Why do I see so many people here recommend microneedling?

109 upvotes 3 years ago

The efficacy of microneedling for hair regrowth as either a stand-alone therapy or adjunct to Minoxidil, and whether Tretinoin is a safer and more effective option. Replies include personal accounts from users who have had success with microneedling in combination with minoxidil and peptide serums, as well as considerations of technique, depth, and potential scarring.

community Scarring Alopecia and NSAIDs?

4 upvotes 5 years ago

The user suspects scarring alopecia and is exploring NSAIDs and turmeric/pepper for inflammation-related hair loss, having experienced burning and thinning with finasteride and testosterone reduction. They are seeking feedback while unable to afford a dermatologist.

community I have tried every hairloss option between shaving and wigs. Considering retrying fin because depression medication also has sexual side effects and hairloss has driven me to almost need them. Every hairloss option I have tried has a "dealbreaker" caveat and so I am forced to choose one of the below

4 upvotes 10 years ago

The user is struggling with hair loss and has tried treatments like finasteride, minoxidil, and hair systems, each with drawbacks. They are considering retrying finasteride before a hair transplant and are advised to seek therapy for mental health support.

community 19M. How many of you see meds as a full solution vs something to be on until more advancements?

6 upvotes 2 months ago

Minoxidil, finasteride, and dutasteride are commonly used for hair loss treatment, with some users seeing them as long-term solutions while awaiting future advancements like hair follicle cloning or gene engineering. Some users also consider additional treatments like anti-inflammatories, PRP, and hair transplants, but remain skeptical about a definitive cure.

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learn Overview

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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