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In Vitro and In Vivo Regulation of SRD5A mRNA Expression of Supercritical Carbon Dioxide Extract from Asparagus Racemosus Root as Anti-Sebum and Pore-Minimizing Active Ingredients

research In Vitro and In Vivo Regulation of SRD5A mRNA Expression of Supercritical Carbon Dioxide Extract from Asparagus racemosus Willd. Root as Anti-Sebum and Pore-Minimizing Active Ingredients

8 citations , February 2022 in “Molecules”

This study found that Asparagus racemosus root extract significantly reduced facial sebum production and pore size in male volunteers, suggesting potential application as an anti-sebum ingredient in cosmetics.

The Cutaneous Side Effects of Selective BRAF Inhibitors and Anti-CTLA4 Agents: The Growing Role of the Dermatologist in the Management of Patients with Metastatic Melanoma

research The Cutaneous Side Effects of Selective BRAF Inhibitors and Anti-CTLA4 Agents: the Growing Role of the Dermatologist in the Management of Patients with Metastatic Melanoma

6 citations , April 2013 in “Current Dermatology Reports”

This review discusses the cutaneous side effects associated with vemurafenib and ipilimumab in metastatic melanoma treatment and emphasizes the importance of dermatologists in managing these skin eruptions; it reports no new clinical results.

research Exploration of Anti-inflammatory Activity of Aquaeous Extract of Hibiscus rosa sinesis (Malvacae)

1 citations , January 2014 in “Research Journal of Pharmacognosy and Phytochemistry”

This study reported that the aqueous root extract of Hibiscus rosa sinesis significantly reduced inflammation in carrageenan-induced paw edema in swiss albino rats.

research Development And Evaluation of Herbal Anti-Dandruff Shampoo Containing Trigonella Foenum-Graecum and Hibiscus Rosa-Sinensis

July 2026 in “Zenodo (CERN European Organization for Nuclear Research)”

This study evaluated a herbal anti-dandruff shampoo containing fenugreek and hibiscus and found it had good cleansing action, stable foam, satisfactory pH, and caused no skin irritation, suggesting it may be an effective alternative to synthetic shampoos.

Preparation of Anti-Dandruff Shampoo from Polyherbal Formulation and Its Antioxidant, Antimicrobial, and Anti-Inflammatory Activity of Aqueous Extract of Different Parts of Azadirachta Indica, Ocimum Tenuiflorum, Eclipta Prostrata, Phyllanthus Emblica, Hibiscus Rosa-Sinensis, and Sapindus Mukorossi - A Novel Approach

research PREPARATION OF ANTI-DANDRUFF SHAMPOO FROM POLY HERBAL FORMULATION AND ITS ANTIOXIDANT, ANTIMICROBIAL AND ANTIINFLAMMATORY ACTIVITY OF AQUEOUS EXTRACT OF DIFFERENT PARTS OF AZADIRACHTA INDICA, OCIMUM TENUIFLORUM, ECLIPTA PROSTRATA, PHYLLANTHUS EMBLICA, HIBISCUS ROSA-SINENSIS, AND SAPINDUS MUKOROSSI-A NOVEL APPROACH

May 2026 in “Zenodo (CERN European Organization for Nuclear Research)”

In this study, researchers developed a polyherbal antidandruff shampoo using medicinal plant extracts and found it exhibited significant antioxidant and antimicrobial properties, including activity against bacteria and fungi linked to scalp infections, suggesting it as a natural alternative to synthetic shampoos.

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Community Join

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community Passive/preventative anti-DHT haircare routine?

in Treatment 2 upvotes 1 year ago

The conversation discusses preventative hair care measures for hair loss, focusing on non-prescription treatments like rosemary, peppermint, castor oils, microneedling, and ketoconazole shampoo. It also touches on the use of finasteride, minoxidil, and RU58841 for those experiencing hair loss.

community I want to add a topical anti androgen to my routine

4 upvotes 2 years ago

RU58841 is considered an effective topical anti-androgen for hair loss, often used with minoxidil. Concerns exist about its purity and sourcing since it's not FDA-approved.

community Results after 3 months of using minoxidil, rosemary oil, and anti-dandruff shampoo.

in Progress Pictures 22 upvotes 9 months ago

The user experienced hair loss potentially due to creatine and stopped using it. They saw progress after three months using minoxidil, rosemary oil, and anti-dandruff shampoo.

community Hair Loss “Cure” for Inflammation: Topical Roflumilast

in Research/Science 32 upvotes 8 months ago

Topical roflumilast is effective for reducing inflammation in various scalp conditions like seborrheic dermatitis, psoriasis, and eczema, but not proven to stop scarring alopecia. Alternatives like apremilast and Vtama are also discussed for their anti-inflammatory benefits.

community Is it worth using anti-hair loss shampoo?

in Product 2 upvotes 7 months ago

Anti-hair loss shampoos, like the one with rosemary, quillaja, and jaborandi extracts, mainly support scalp health but are not effective for hair regrowth compared to treatments like finasteride or minoxidil. Ketoconazole 2% is noted as the only effective anti-hair loss shampoo, while others are often considered scams.

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Learn

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learn Rosemary

herb and oil with stimulant, circulatory, anti-inflammatory and antioxidant properties

learn Minoxidil

An essential vasodilator with some anti-androgenic effects

learn Spironolactone

powerful topical and oral anti-androgen used mostly by women

learn Ketoconazole

antifungal with some anti-androgenic benefits, often used as a shampoo

learn Metformin

diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

learn GT20029

What is GT20029 and how does it work as a topical anti-androgen for hair loss? GT20029 is a topical anti-androgen that degrades androgen receptors to combat hair loss.

learn Aminexil

Aminexil: Can I combine it with anti-hair loss shampoos or will it lose effectiveness? You can safely combine Aminexil with anti-hair loss shampoos for enhanced effectiveness.

learn Cetirizine

What makes cetirizine a unique anti-inflammatory option for your scalp? Laboratory work reports that cetirizine lowers PGD2 and other inflammatory mediators, which is why researchers have proposed it for the scalp. There is no approved topical product and the clinical evidence is one small unblinded pilot study in pattern hair loss, so scalp use is off-label and experimental.

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Clinics

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Experts

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16
Dermatologist
Andi Iryanti, M. Biomed
Indonesia

Andi Iryanti, M. Biomed