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research Anti-PDGF receptor β antibody-conjugated squarticles loaded with minoxidil for alopecia treatment by targeting hair follicles and dermal papilla cells

17 citations , May 2015 in “Nanomedicine: Nanotechnology, Biology and Medicine”

This study found that lipid nanocarriers called squarticles, conjugated with an antibody, enhanced minoxidil uptake in dermal papilla cells, potentially improving alopecia treatments.

research PDGF isoforms induce and maintain anagen phase of murine hair follicles

136 citations , June 2006 in “Journal of Dermatological Science”

This study found that injecting PDGF-AA and -BB into mouse skin immediately triggered the hair growth cycle's anagen phase, suggesting potential treatment options for certain types of alopecia.

research Hair growth stimulated by conditioned medium of adipose-derived stem cells is enhanced by hypoxia: evidence of increased growth factor secretion

134 citations , January 2010 in “Biomedical research”

This study found that subcutaneous administration of conditioned medium from adipose-derived stem cells promoted hair growth in mice, and hypoxia enhanced this effect by altering growth factor secretion.

research Rebamipide Induces Hair Regeneration Through EP4-Driven Lipid Metabolism Remodeling

October 2025 in “International Journal of Molecular Sciences”

This study found that topical rebamipide, originally a gastric ulcer medication, can activate hair follicle stem cells and promote hair regeneration by modulating dermal adipocyte metabolism, with potential targeting of the prostaglandin E receptor EP4.

research Targeting integrin pathways: mechanisms and advances in therapy

54 citations , January 2023 in “Signal Transduction and Targeted Therapy”

This review examines integrins as pharmacological targets, discussing current integrin-based therapies and emphasizing the need to understand integrin mechanisms for successful drug development, without reporting new clinical results.

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community Surprisingly thorough study on He-Shou-Wu/Fo Ti

13 upvotes 3 years ago

He Shou Wu (Fo Ti) extract was found to prolong the hair growth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.

community My derm said they came up with a new serum that is better then fin? What’s y’all’s thoughts

8 months ago

A new serum claims to enhance hair regrowth by amplifying oxygen delivery, improving the effectiveness of treatments like exosomes and peptides. Users are skeptical, questioning its efficacy compared to established treatments like Minoxidil and Finasteride.

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learn Beta Polypeptide

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