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      learn Pyrilutamide

      highly targeted anti-androgen that might have minimal systemic effects

      learn Spironolactone

      powerful topical and oral anti-androgen used mostly by women

      learn Cyproterone

      a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

      learn RU58841

      a potent but unapproved and potentially problematic topical anti-androgen

      learn Azelaic Acid

      acid used for antimicrobial, anti-inflammatory and anti-androgenic properties

    Research

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      community New Study - Flavonoids More Effective Than Finasteride?

      in Research/Science  148 upvotes 11 months ago
      A recent publication suggests that the flavonoids eriocitrin and silymarin may be more effective than finasteride in binding to the enzyme responsible for hair loss. People in the conversation are skeptical about the effectiveness and safety of these flavonoids until tested on humans, and some discuss their personal experiences with other treatments.

      community The New, Improved CB-03-01/Setipiprant Group Buy

       29 upvotes 8 years ago
      The group buy for CB-03-01, a topical anti-androgen for hair loss, was postponed and refunded due to issues with the product's form and solubility. The product, also known as Breezula, is an alternative to finasteride with fewer side effects, but its official release is delayed until 2021.

      community He used Dutasteride for 20 years. Interview

      in Treatment  111 upvotes 1 week ago
      Dutasteride has been used for 20 years with some hair thickness improvement but no dramatic regrowth. The user also experimented with minoxidil, tretinoin, and peptides like BPC 157 for potential benefits in hair density and quality.
      The story of RU58841/ PSK3841

      community The story of RU58841/ PSK3841

      in Research  622 upvotes 3 months ago
      RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.

      community why hair restoration has not been progressed for last 20 years?

      in Chat  31 upvotes 1 year ago
      The conversation discusses the lack of significant advancements in hair loss treatments beyond finasteride and minoxidil, questioning if hair restoration technology has reached a dead end. Hair transplant technology has improved, but new medications face challenges with market entry, cost, accessibility, and long-term effectiveness.