93 citations
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May 2002 in “Journal of Investigative Dermatology” This study found that chronic ultraviolet-B exposure increased skin vascularization and wrinkle formation in mice, while overexpressing the angiogenesis inhibitor thrombospondin-1 reduced these effects, suggesting angiogenesis inhibition as a potential approach to prevent photo-damage.
322 citations
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January 1997 in “Thrombosis and Haemostasis” This review discusses factors influencing angiogenesis, focusing on vascular permeability factor as a key inducer and thrombospondin as a notable inhibitor, and recommends exploring molecular mechanisms for therapeutic interventions.
15 citations
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March 2007 in “BioTechniques” This study introduced a new in vivo angiogenesis assay using Gelfoam implanted in ND-GFP transgenic mice to efficiently identify angiogenesis stimulators and inhibitors through GFP visualization.
June 2025 in “Phytomedicine” The formula may improve hair growth and health by boosting blood flow and reducing cell stress.
164 citations
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December 2000 in “Journal of Dermatological Science” This review explores mechanisms of skin angiogenesis and suggests targeting blood vessels as a promising therapy for skin diseases, but it reports no new research results.