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research Correlations between hormonal intrauterine devices and androgenic skin conditions: A retrospective cohort study

2 citations , February 2022 in “Journal of The American Academy of Dermatology”

This study found that hormonal IUD implantation was associated with an increased risk of acne vulgaris but a decreased risk of hirsutism, alopecia, and rosacea compared to nonhormonal copper IUDs.

research URTICA DIOICA EXTRACT DOWNREGULATES THE GENE EXPRESSION OF 5Α-RII IN HACAT CELLS: POSSIBLE IMPLICATIONS AGAINST ANDROGENIC SKIN DISEASES.

1 citations , January 2023 in “PubMed”

In this study, Urtica dioica extract was found to significantly downregulate 5-alpha-reductase type II gene expression in skin cells, suggesting potential usefulness against androgenic skin diseases.

research Conditions simulating androgenetic alopecia

6 citations , January 2015 in “Journal of The European Academy of Dermatology and Venereology”

This review examines various conditions that resemble androgenetic alopecia, analyzing their pathogenesis and highlighting the difficulties they pose for accurate diagnosis and treatment; it reports no clinical results.

research Clinical and epidemiological characteristics and condition of the hormonal status in women with androgenetic alopecia (1139.3)

April 2014 in “The FASEB Journal”

This study examined 12 women with androgenetic alopecia and found that many had other symptoms linked to hyperandrogenism, suggesting the importance of further hormone level investigations.

research Melatonin in Dermatologic Allergic Diseases and Other Skin Conditions: Current Trends and Reports

1 citations , February 2023 in “International Journal of Molecular Sciences”

This review discusses various therapeutic roles of melatonin, particularly its antioxidant and sleep-regulating properties, for skin and scalp conditions, and reports no new clinical results.

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Community Join

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community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

63 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community Theoretically won't this be better than finasteride? Azelaic acid + zinc

9 upvotes 3 years ago

The conversation discusses using zinc sulphate and azelaic acid to inhibit 5 alpha-reductase activity, which could potentially treat androgen-related skin conditions like hair loss. Combining these with vitamin B6 could enhance the effect, potentially offering an alternative to finasteride.

community DHT Itch is real. The connection between Acne and Male Pattern Baldness shows this

in Research/Science 64 upvotes 3 years ago

The conversation discusses the link between seborrheic dermatitis, acne, and male pattern baldness, suggesting that DHT may cause both skin conditions and hair loss. Treatments mentioned include RU58841, finasteride, dutasteride, minoxidil, Nizoral shampoo, and other topical anti-androgens.

community Hair repigmentation of poliosis circumscripta in androgenetic alopecia patient treated with exosomes and fractional picosecond laser

2 upvotes 2 years ago

Exosomes combined with fractional picosecond laser treatment were effective in treating androgenetic alopecia and promoting repigmentation in white hair patches. The role of exosomes in hair repigmentation, particularly in conditions like poliosis, is not well-studied.

community Losing Hair on Dutasteride? You might have LPP

96 upvotes 1 year ago

Men with hair loss might have lichen planopilaris (LPP), which can mimic androgenetic alopecia, leading to misdiagnosis and ineffective treatment with finasteride or dutasteride. Proper diagnosis, including biopsies, is crucial to distinguish between androgenetic alopecia and conditions like LPP.

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Learn

6 / 47 results

learn Ketoconazole

antifungal with some anti-androgenic benefits, often used as a shampoo

learn Cyproterone

a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

learn Microneedling

technique to create small wounds in skin to activate collagen production and hair growth

learn Clascoterone

a novel topical treatment that inhibits DHT on androgen receptors

learn Azelaic Acid

acid used for antimicrobial, anti-inflammatory and anti-androgenic properties

learn GHK-Cu

What is GHK-Cu and why is it said to be a "miracle" for hair? GHK-Cu is a copper peptide studied mainly for wound healing and skin repair; for hair loss the evidence stops at cell-culture and animal work, and no published human trial has tested it for androgenetic alopecia.

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Experts

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SMP Specialist
Noelle Skin
Nice, France

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Noelle Skin