56 citations
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September 2013 in “Journal of Biochemistry and Molecular Biology” This study observed that androgen treatment increased ROS production and TGF-β1 secretion in rat hair follicle dermal papilla cells, suggesting that the androgen-induced TGF-β1 is mediated by ROS.
This study found that in men with androgenetic alopecia, nitric oxide synthase protein expression was significantly higher at androgenetic sites compared to non-androgenetic sites or those of healthy controls, suggesting a possible role in hair follicle regulation.
8 citations
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October 2002 in “Journal Of Clinical Periodontology” This study suggests that levamisole and finasteride can significantly reduce DHT levels in human gingival fibroblasts, potentially addressing phenytoin-induced gingival overgrowth.
1 citations
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January 2006 This article reviews the pathophysiology and causes of androgen-mediated hair growth in hirsutism but does not report any clinical outcomes; treatment aspects are discussed separately.
4 citations
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November 2015 in “Journal of Investigative Dermatology” This study found that filamin A plays a crucial role in fibroblasts' ability to sense and respond to mechanical stimuli, significantly affecting wound closure and fibroblast-mediated processes in mice.