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Did you mean Androgen Receptor mRNA?

Glossary Androgen Receptor mRNA

carries genetic instructions to produce the androgen receptor protein

Androgen Receptor mRNA (AR mRNA) is the messenger RNA that carries the genetic instructions from DNA to produce the androgen receptor protein. This protein binds to androgens, which are hormones like testosterone, and plays a crucial role in the development and maintenance of male characteristics, as well as in conditions like androgenetic alopecia (pattern hair loss).

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Research

5 / 1000+ results

research Increased androgen receptor messenger RNA in frontal-parietal hair follicles of women with androgenetic alopecia

6 citations , January 2013 in “Genetics and Molecular Research”

This study found that women with androgenetic alopecia demonstrated higher androgen receptor gene expression compared to controls, with a correlation found between higher AR expression and fewer CAG repeats in the AR gene.

research Use of genetics in the prediction of success in male pattern hair loss therapy and mechanistic studies

February 2026 in “Frontiers in Pharmacology”

This review suggests a shift toward genetically informed treatments for male pattern hair loss by integrating genetic insights and pharmacogenetic markers into therapeutic decision-making.

research Updates in Treatment for Androgenetic Alopecia

January 2025 in “Annals of Dermatology”

This review discusses current and emerging treatments for androgenetic alopecia, covering mechanisms, efficacy, and safety of both androgen-targeted and non-androgen-targeted approaches, but reports no new clinical results.

research Genomic Markers and Personalized Medicine in Androgenetic Alopecia: A Comprehensive Review

August 2024 in “Cosmetics”

This review discusses genetic and pharmacogenetic insights, along with RNA interference technologies, for developing personalized therapies for androgenetic alopecia, yet presents no new clinical results.

research Androgen receptors and their biology

66 citations , January 2001 in “Vitamins and hormones”

This chapter reviews the role of androgen receptors in mediating the actions of androgens in specific tissues and provides no new experimental findings.

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Community Join

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community Quit vaping/smoking = 80% less loss

in Research/Science 235 upvotes 2 years ago

Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

community Dht is a real bastard of a hormone it’s annoying to get rid of it

335 upvotes 5 days ago

DHT affects hair loss and hormonal balance, with treatments like finasteride, dutasteride, and minoxidil being discussed. Users share experiences with side effects, gym performance, and the impact on libido, with some suggesting complex treatment regimens.

community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth

211 upvotes 1 year ago

PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.

community Pelage PP405: New Hair Growth from Inactive Follicular Units - Phase 2a results at AAD 2026

1080 upvotes 6 months ago

PP405, a topical treatment, shows promise for hair growth by activating inactive follicles, with 66% of participants experiencing positive results. The treatment is well-tolerated and may proceed directly to Phase 3 trials, offering a potential alternative to minoxidil and finasteride.

community Having androgen receptor density and sensitivity at wrong f*ing place

in Satire 7 upvotes 1 year ago

The conversation discusses hair loss treatments, focusing on the use of topical minoxidil, microneedling, finasteride, and dutasteride, while debating the role of testosterone and DHT in hair loss. It also touches on the potential liver health impacts of these treatments and the genetic sensitivity of hair follicles to androgens.

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Experts

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Trichologist
Andrew Messenger
London, England, United Kingdom
17+ yrs

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Andrew Messenger