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research Comparison of Hair Follicle Density and Anagen:Telogen Ratio between Topical Minoxidil Alone and Its Combination with Platelet-Rich Plasma Exosomes in a Mice Model of Androgenetic Alopecia

May 2026 in “Malaysian Journal of Medicine and Health Sciences”

This study found that in a testosterone-induced androgenetic alopecia mouse model, the combination of PRP-derived small extracellular vesicles and 5% minoxidil significantly improved hair follicle density and the anagen-to-telogen ratio compared to minoxidil alone, suggesting a synergistic effect that enhances hair growth.

A 2% Oleosome-FGF-2 Fusion Extract Scalp Serum Improves Hair Density, Anagen/Telogen Ratio, Hair Shaft Thickness, and Scalp Barrier in Women with Shedding-Prone Hair: A Randomized, Single-Blind, Placebo-Controlled Pilot Study

research A 2% Oleosome-FGF-2 Fusion Extract Scalp Serum Improves Photo-trichogramDerived Hair Density, Anagen/Telogen Ratio, Hair Shaft Thickness, and Scalp Barrier Parameters in Women with Shedding-Prone Hair: A Randomized, SingleBlind, Placebo-Controlled Pilot Study

July 2026 in “International Journal of Clinical & Experimental Dermatology”

This exploratory pilot study reported that using a 2% Oleosome-FGF-2 fusion extract scalp serum twice daily for 84 days in women with telogen effluvium and brittle hair improved hair density, anagen/telogen ratio, hair shaft thickness, and scalp hydration compared to a placebo.

Effects of Platelet-Rich Plasma on Hair Follicle Count and Hair Ratios in Androgenic Alopecia: Alone or Combined with Other Treatments

research Effects of platelet-rich plasma application on hair follicle count, telogen/anagen ratio, and miniaturized hair ratio in patients with androgenic alopecia: alone or in combination with other treatments

July 2025 in “Journal of Dermatological Treatment”

This study found that platelet-rich plasma significantly improved hair growth parameters in androgenic alopecia patients and was even more effective when combined with minoxidil, particularly in reducing vellus hair.

research Finasteride increases anagen hair in men with androgenetic alopecia

129 citations , October 2000 in “British Journal of Dermatology”

This study found that finasteride increases anagen hair growth in men with androgenetic alopecia.

research Amaranthus Extract Promotes Healthy Follicles and Anagen Hair Density-A Randomized Placebo-Controlled, Double-Blinded Study.

October 2025 in “PubMed”

This study found that applying amaranthus extract cream to the scalp significantly improved terminal hair density, anagen hair count, and pilary index in men with male pattern hair loss, suggesting it may be a safe and effective supportive therapy.

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Community Join

5 / 381 results

community My Theory Of Androgenic Alopecia

16 upvotes 9 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

community Effectiveness and Safety of Hair Growth Formulation Containing Tectona grandis L.f (Teak) Leaf Extract

in Chat 33 upvotes 1 year ago

Teak leaf extract shows potential as a mild hair growth promoter for androgenic alopecia, with similar positive trends to minoxidil but without significant side effects. It can be made at home using dried teak leaves and ethanol, though its effectiveness compared to other treatments like finasteride is debated.

community Creatine Doesn’t Cause Hair Loss: Stop the BS

137 upvotes 11 months ago

Creatine does not cause hair loss, despite many users reporting personal experiences of hair shedding. Scientific evidence shows no link between creatine and increased hair loss or hormone changes.

community How dutasteride makes hair loss impossible

in Chat 142 upvotes 1 year ago

Dutasteride is discussed as a treatment that makes hair loss impossible, with some users sharing experiences of hair regrowth and side effects. Finasteride and oral minoxidil are also mentioned as treatments, with concerns about side effects and effectiveness.

community Dht kills hair, but no one says why?

in Finasteride/Dutasteride 40 upvotes 1 year ago

DHT affects hair follicles, contributing to hair loss, but the exact mechanism is unclear. Treatments like finasteride and minoxidil are used to manage hair loss, though they may have side effects and varying effectiveness.

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Learn

8 / 25 results

learn Caffeine

Does caffeine stimulate hair growth or only slow hair loss? Caffeine stimulates hair follicles in laboratory cultures, and one open-label trial in 210 men found a 0.2% caffeine topical non-inferior to minoxidil 5% on an anagen-ratio endpoint; there is no placebo-controlled evidence that it regrows hair, and none at all in alopecia areata or telogen effluvium.

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Overview

learn Fluridil

a topical anti-androgen with less systemic involvement

learn Beta Polypeptide

learn Thymosin Beta 4

learn Omega 3

Is the omega-3 to omega-6 ratio in your diet feeding your hair problem without you knowing? Nutrition sources describe a lopsided omega-6 to omega-3 intake as pro-inflammatory, but no published human study shows that the dietary ratio changes 5-alpha reductase, scalp DHT or hair loss; the one relevant trial tested a commercial omega-3/6 plus antioxidant supplement in 120 women, not a change in dietary fat ratio.

learn Procyanidin

Are Procyanidin based hair tonics or shampoos effective against androgenic alopecia? Procyanidin-based hair tonics may promote hair growth but lack definitive evidence for AGA.

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Clinics

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Experts

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