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research Immunohistochemical analysis of tissue remodelling during the anagen-catagen transition of the human hair follicle

47 citations , July 1997 in “British Journal of Dermatology”

This research observed that during the catagen phase, the inner root sheath of hair follicles becomes an early target, highlighting its potential role in maintaining hair follicle homeostasis.

research Immunohistochemical analysis of tissue remodelling during the anagen—catagen transition of the human hair follicle

23 citations , July 1997 in “British Journal of Dermatology”

This study suggests that the inner root sheath plays a significant role in maintaining hair follicle homeostasis during the catagen phase's early stages.

research Hair follicle transcriptome profiles during the transition from anagen to catagen in Cashmere goat (Capra hircus)

14 citations , January 2015 in “Genetics and molecular research”

This study found that numerous genes involved in hair growth, including 73 co-up-regulated ones, were differentially expressed in goat hair follicles during the hair growth cycle.

research Igf1r signalling acts on the anagen‐to‐catagen transition in the hair cycle

20 citations , January 2017 in “Experimental Dermatology”

In this study, deleting the Igf1 receptor in specific skin cells of mice affected hair follicle cycling but not overall skin health, suggesting Igf1r's role in hair cycle regulation through Bmp-4 activation.

research Hair-Cycle-Dependent Expression of Parathyroid Hormone-Related Protein and its Type I Receptor: Evidence for Regulation at the Anagen to Catagen Transition

52 citations , May 2003 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study found that overexpression of parathyroid hormone-related protein in mice resulted in 30–40% shorter hair due to premature transition into the catagen phase of the hair cycle.

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Community Join

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community IGFBP‐rP1 is a potential therapeutic target in androgenic alopecia

in Research/Science 13 upvotes 1 year ago

IGFBP‐rP1 shows potential for treating androgenic alopecia by influencing hair cycle transitions. Increasing IGF-1 levels may have similar effects to Minoxidil and 5-AR inhibitors in reducing hair loss.

community PP405 Won’t Work: Follicle Is Miniaturized, Fibrosed, And Missing Key Support Cells

7 months ago

PP405 is ineffective for miniaturized, fibrosed hair follicles in androgenetic alopecia. AMP303 may activate hair follicle stem cells, but minoxidil and finasteride are still the main treatments.

community Bryan Johnson's email regarding hair loss and his protocol (including why he doesn't take Fin or Dut).

in Research/Science 6 upvotes 5 months ago

Hair loss treatments include topical and oral minoxidil, low-level laser light therapy, and peptide serums. Bryan Johnson avoids finasteride and dutasteride due to potential side effects, focusing instead on his own protocol with these treatments.

community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth

211 upvotes 1 year ago

PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.

community Predict if You'll Shed and Responding to Treatment: Ultrasound Imaging Technology

18 upvotes 1 year ago

Ultrasound imaging can predict hair shedding and assess hair growth stages by analyzing hair follicle characteristics. The conversation also discusses using ultrasound for personal hair analysis and mentions the potential use of infrared emission for hair treatment.

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Learn

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learn Exosomes

Tiny cell-derived particles offered by clinics as an injectable treatment

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Experts

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Clinics

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