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    Did you mean 5-alpha-reductase inhibitor?
    Glossary 5-alpha-reductase inhibitor

    blocks enzyme converting testosterone to dihydrotestosterone (DHT)

    A 5-alpha-reductase inhibitor is a type of medication that blocks the enzyme 5-alpha-reductase, which is responsible for converting testosterone into dihydrotestosterone (DHT). By reducing DHT levels, these inhibitors can help treat conditions like male pattern baldness and benign prostatic hyperplasia (BPH).

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    Research 10 of 1000+

    1. The 5-alpha reductase inhibitor finasteride reduces dyskinesia in a rat model of Parkinson’s disease Experimental Neurology · 2017 · 15 citations
    2. 5-Alpha-Reductase Inhibitors and Combination Therapy Urologic Clinics of North America · 2016 · 15 citations
    3. Efficacy and safety of Finasteride (5 alpha-reductase inhibitor) monotherapy in patients with benign prostatic hyperplasia: A critical review of the literature Archivio Italiano di Urologia e Andrologia · 2020 · 14 citations
    4. Impact of Alpha Blockers, 5-alpha Reductase Inhibitors and Combination Therapy on Sexual Function Current Urology Reports · 2014 · 11 citations
    5. Analysis of breast health outcomes in women on oral 5-alpha reductase inhibitors: A single-center retrospective cohort study Journal of the American Academy of Dermatology · 2024 · 6 citations
    6. The Risk of Venous Thromboembolism (VTE) in Men with Benign Prostatic Hyperplasia Treated with 5-Alpha Reductase Inhibitors (5ARIs). Clinical Epidemiology · 2021 · 6 citations
    7. Intraethnic variation in steroid-5-alpha-reductase polymorphisms in prostate cancer patients: a potential factor implicated in 5-alpha-reductase inhibitor treatment 2015 · 4 citations
    8. IsoPSA Performance Characteristics are Unaffected by 5-Alpha Reductase Inhibitors or Alpha-Blockers: Results From the IsoPSA Validation Study Urology · 2023 · 2 citations
    9. Analysis of Data From Breast Diseases Treated With 5-Alpha Reductase Inhibitors for Benign Prostatic Hyperplasia Clinical Breast Cancer · 2019 · 1 citations
    10. No Increased Cardiovascular Hazard with Oral 5-Alpha-Reductase Inhibitors in Treatment of Androgenetic Alopecia: A TriNetX Retrospective Cohort Study Journal of the American Academy of Dermatology · 2026
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    Community 10 of 282

    1. Does caffeine inhibit 5-α-reductase? Reddit · 27 Dec 2019
    2. BREAKTHROUGH: I’m a radiochemist and discovered a radioactive isotope scalp serum that OUTPERFORMS Minoxidil and 5-AR inhibitors! (Lab Data Inside) Reddit · 10 Jun 2025
    3. Allopregnanolone deficiency by 5-ari inhibition (fin/dut users) Reddit · 11 Dec 2023
    4. Why does this industry still revolve around 5-AR inhibitors? Reddit · 14 Jun 2021
    5. Did anybody use beta sisterol for hair loss? I saw in many articles in the internet that said that beta sisterol blocks dht by inhibiting 5a reductase type 2 enzyme and some reviews of people who said that it worked better than saw palmetto in terms of stoping hair loss and helping prostate. Reddit · 11 May 2023
    6. Which Saw Palmetto is good for blocking 5 alpha reductase, Serenoa repens or Chamaerops humilis? Reddit · 26 Jun 2020
    7. 4 months on oral dutasteride + one month and 3 weeks on topical minoxidil 5% Reddit · 23 May 2026
    8. Three months 0.5mg Dutasteride and 5% topical Minoxidil daily Reddit · 22 May 2026
    9. Minoxidil is a 5ar inhibitor according to research Reddit · 4 Oct 2025
    10. A better treatment would be a localized 5ar inhibitor that breaks down when it enters blood or leaves hair follicle Reddit · 13 May 2025
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    Learn 6 of 10

    1. Dutasteride 5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride
    2. Finasteride Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically
    3. Saw Palmetto Palm-berry extract taken as a supplement
    4. Azelaic Acid Acid used in acne and rosacea creams
    5. Rosemary Herb whose oil is used in hair care
    6. Neem Oil Oil from the neem tree, used in traditional remedies
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