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    Did you mean Alpha-adrenergic antagonists?
    GlossaryAlpha-blockers (Alpha-adrenergic antagonists)

    medications that relax blood vessels by blocking norepinephrine

    Alpha-blockers, also known as alpha-adrenergic antagonists, are medications that relax certain muscles and help small blood vessels remain open. They work by blocking the action of norepinephrine, a hormone that tightens the muscles in the walls of smaller arteries and veins. This can improve blood flow and lower blood pressure, making them useful in treating conditions like hypertension and benign prostatic hyperplasia (BPH).

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      community The truth about Dutasteride (w/ sources)

      in Finasteride/Dutasteride  52 upvotes 2 years ago
      The effectiveness of Dutasteride compared to Finasteride in treating hair loss, with evidence given such as studies and experiences, as well as discussion around whether one should switch from Finasteride to Dutasteride. There is also a discussion on post-Dutasteride syndrome.

      community Approximately 1 month on oral dut+ oral min

      in Progress Pictures  103 upvotes 1 year ago
      A user shared progress pictures after one month on oral dutasteride and minoxidil, noting some improvement despite initial shedding. They previously used finasteride for a year without noticeable change and emphasized the importance of photo comparisons.

      community Why is dutasteride's volume of distribution so much bigger than finasteride? Is it more lipophilic and crosses barriers better?

      in Finasteride/Dutasteride  24 upvotes 9 months ago
      Dutasteride has a larger volume of distribution than finasteride due to its lipophilic nature, allowing it to concentrate in hydrophobic areas and making it difficult to excrete. A user experiencing hair loss has been using oral finasteride for 10 months with minimal regrowth and is considering switching to dutasteride or adding oral minoxidil.

      community 8 years of hair loss, turning 30 next month

      in Progress Pictures  150 upvotes 3 months ago
      The user has been dealing with hair loss for 10 years, worsened by psoriasis, and uses minoxidil and finasteride. They seek advice on managing psoriasis and hair loss, with suggestions to see a dermatologist, try different shampoos, and be patient.

      community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

      in Research/Science  92 upvotes 3 years ago
      The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.