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research Role of Allopregnanolone Biosynthesis in Acute Stress-Induced Anxiety-Like Behaviors in Mice

19 citations, May 2017 in “Synapse”

Blocking allopregnanolone production in mice makes them more anxious after stress, but this can be reversed with a drug that mimics allopregnanolone.

research Benzothiazepines, Diltiazem, and JTV-519 Exert Anxiolytic-Like Effects via Neurosteroid Biosynthesis in Mice

1 citations, March 2020 in “Journal of Pharmacological Sciences”

Benzothiazepines like diltiazem reduce anxiety in mice by making neurosteroids.

research Role of Neurosteroid Allopregnanolone on Age-Related Differences in Exercise-Induced Hypoalgesia in Rats

4 citations, November 2018 in “Journal of pharmacological sciences”

Mild exercise reduces pain in older rats through a brain chemical, while intense exercise reduces pain in all rats through a different pain-blocking process.

Treatment With and Withdrawal From Finasteride Alter Ethanol Intake Patterns in Male C57BL/6J Mice: Potential Role of Endogenous Neurosteroids

research Treatment With and Withdrawal From Finasteride Alter Ethanol Intake Patterns in Male C57BL/6J Mice: Potential Role of Endogenous Neurosteroids

54 citations, August 2005 in “Alcohol”

Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.

research Cytoprotective Effects of Paeoniflorin Are Associated with Translocator Protein 18 kDa

3 citations, July 2018 in “Biomedicine & pharmacotherapy”

Paeoniflorin protects brain cells by involving a specific protein and neurosteroids.

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Community Join

5 / 9 results

community 1.5 years of Fin, switch 3 months ago to Dut, with 5 moths of Min too

in Progress Pictures 104 upvotes 2 years ago

User switched from Fin to Dut for better hair loss results, using 0.5mg Dut and 1ml Min daily. Some discuss potential side effects and benefits of Dut compared to Fin.

community Debunking the "Adverse metabolic consequences of dutasteride"

in Research/Science 40 upvotes 3 years ago

Dutasteride is more effective than finasteride, has neuroprotective benefits, and may prevent acne. Despite initial concerns about metabolic effects, further research suggests it is safe for most users, especially if not hypogonadal.

community safety of and efficiency of anti androgens for women

in Female 6 upvotes 2 years ago

27F with androgenic alopecia since 17 seeks treatment. Tried spironolactone, caused low blood pressure; believes finasteride is safer and wants to try it.

community Glycine supplementaion is said to strongly upregulate 5-alpha Reductase (5-ar) Activity

in Research/Science 15 upvotes 4 years ago

Glycine supplementation may increase 5-alpha reductase activity, potentially affecting hair loss. Users discuss its impact on hair fall and its role in the body.

community Is there a topical androgen receptor blocker so we don't have to fuck with the enzyme and destroy our allopregnanolone, but go and hit the end target straight?

in Treatment 47 upvotes 5 months ago

The conversation discusses topical androgen receptor blockers for hair loss, mentioning Clascoterone, Pyrilutamide, GT20029, and RU58841. Ketoconazole's effectiveness and application methods are also debated.

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