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GlossaryG allele

specific gene variant with guanine at a particular DNA position

An allele is a variant form of a gene, and the "G allele" refers to a specific version of a gene where the nucleotide guanine (G) is present at a particular position in the DNA sequence. In genetics, identifying the presence of a G allele can help determine certain traits or susceptibilities to conditions, as different alleles can influence how genes are expressed and how they function in the body.

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Genetic Variants and Lifestyle Factors in Androgenetic Alopecia Patients: A Case-Control Study of Single Nucleotide Polymorphisms and Their Contribution to Baldness Risk

research Genetic Variants and Lifestyle Factors in Androgenetic Alopecia Patients: A Case-Control Study of Single Nucleotide Polymorphisms and Their Contribution to Baldness Risk

January 2025 in “Nutrients”

Genetic factors and diet significantly increase the risk of male pattern baldness.

research Uncovering the Genetic Architecture and Evolutionary Roots of Androgenetic Alopecia in African Men

March 2025 in “Human Genetics and Genomics Advances”

Genetic predictions of baldness in Europeans don't apply well to African men.

research Gene-Wide Association Study Between the Aromatase Gene (CYP19A1) and Female Pattern Hair Loss

77 citations , April 2009 in “British Journal of Dermatology”

Aromatase gene variation may increase female hair loss risk.

research Identification of the Keratin-Associated Protein 22-2 Gene in Capra Hircus and Its Association with Cashmere Traits

1 citations , September 2023 in “Animals”

A new goat gene affects cashmere fiber thickness; certain variations can make the fibers coarser.

research Prevalence of MMP-1 rs1799750 Polymorphism in Androgenetic Alopecia: A Cross-Sectional Study in an Indonesian Population

November 2025 in “Molecular and Cellular Biomedical Sciences”

There is no significant link between the MMP-1 rs1799750 polymorphism and androgenetic alopecia in the Indonesian population.

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community DHT levels after 4 weeks of Fina and 8 weeks of Fina + 4 weeks of Duta

in Update 35 upvotes 6 years ago

The user reported early stage diffuse hair thinning and increased DHT levels after 4 weeks on Finasteride and 8 weeks on Finasteride plus 4 weeks on Dutasteride, despite the medications being authentic and stored properly. They are considering increasing their Dutasteride dosage due to the lack of side effects and are unsure if the treatment is helping their hair.

community My Theory Of Androgenic Alopecia

in Research/Science 19 upvotes 3 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

community 3 months progress!! Fin + Min + Derma roller + Nizoral Shampoo.

in Progress Pictures 564 upvotes 2 years ago

The post discusses a user's successful hair regrowth after 3 months using 1 mg oral finasteride, oral minoxidil, weekly 1.5mm derma rolling, and Nizoral shampoo every other day, with no side effects. The conversation includes various responses, questions about the user's ethnicity and previous scalp condition, and suggestions for topical treatments.

community Chromosome 20’s balding effects and why fin likely isn’t working for some.

in Treatment 96 upvotes 6 months ago

Finasteride is effective for DHT/AR-driven hair loss but not for chromosome 20-driven cases, where treatments like minoxidil, prostaglandin analogs, and low-level laser therapy may be more beneficial. Genetic testing can help determine the underlying cause of hair loss to tailor treatment effectively.

community 36 year old. 18month moxidil and fin.

in Progress Pictures 732 upvotes 1 year ago

A 36-year-old has been using 1mg oral finasteride daily and minoxidil foam twice daily for 18 months, experiencing significant hair regrowth with no side effects. Initial shedding occurred, but noticeable improvements began around 11 months, with major changes by 16 months.

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