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research Age-Related Hair Pigment Loss

20 citations , January 2015 in “Current problems in dermatology”

This paper reviews recent research on hair graying, suggesting that an imbalance in oxidative stress handling may affect melanocyte stem cells and melanin production with age, and calls for exploring strategies to prolong melanin production.

research A Study on Gender- and Age-Related Differences in SMP (Scalp Micropigmentation) Status Perception and Side-Effect Awareness

December 2025

This study found that perceptions of scalp micropigmentation and awareness of its side effects vary significantly by gender and age, influencing attitudes and intentions toward the procedure.

research Trichoscopic Findings of Hair Loss in Koreans

16 citations , January 2015 in “Annals of Dermatology”

In this study, trichoscopic features aiding differential diagnosis of alopecia in Korean patients were found to be similar to those in Caucasians, but pigment pattern frequencies differed due to racial characteristics.

research The role of PEDF in ageing and development: reduction of oxidative damage and support for stem cells

November 2025 in “Journal of Pharmacy and Pharmacology”

This review highlights pigment epithelium-derived factor's roles in ageing and development, focusing on its antioxidant functions and support of stem cell survival, but reports no new experimental results.

research Stable analytic extrapolations in the theory of strong interactions

January 1974 in “OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)”

This study found that hair follicle melanocytes show increased age-related susceptibility to oxidative stress compared to epidermal melanocytes, which may contribute to the graying of hair.

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community The Role of Astaxanthin as a Nutraceutical in Health, Age-Related Conditions and Hair Loss

3 upvotes 3 years ago

Astaxanthin (ASX) is highlighted as a promising supplement for treating hair loss due to its antioxidant properties. It may help with inflammation and oxidative stress, which are linked to hair loss and aging.

community Prevention of age-related beard graying in humans by the topical application of Eriodictyon angustifolium extract

5 upvotes 4 years ago

Topical application of Eriodictyon angustifolium extract can prevent and reverse age-related beard graying and darken gray hair by increasing melanin production. Sterubin, a component of the extract, also promotes hair pigmentation and protects cells from DNA damage.

community Dht kills hair, but no one says why?

in Finasteride/Dutasteride 40 upvotes 1 year ago

DHT affects hair follicles, contributing to hair loss, but the exact mechanism is unclear. Treatments like finasteride and minoxidil are used to manage hair loss, though they may have side effects and varying effectiveness.

community Story time! The Great Unbalding (PP405)

230 upvotes 11 months ago

PP405 is a promising new hair loss treatment that may reactivate dormant hair follicles without side effects. It could surpass traditional treatments like minoxidil and finasteride if successful in further trials.

community How far are we from a treatment better than finasteride?

in Treatment 129 upvotes 1 year ago

Dutasteride is more effective than finasteride for hair loss as it blocks more of the enzyme causing hair loss. New treatments like stem cell therapies and alternatives to minoxidil are being explored, but major advancements are still years away.

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