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Glossary Adrenocorticotropic Hormone

hormone stimulating adrenal glands to release cortisol

Adrenocorticotropic Hormone (ACTH), also known as corticotropin, is a hormone produced by the pituitary gland that stimulates the adrenal glands to release cortisol, a crucial stress hormone. This hormone plays a key role in regulating metabolism, immune response, and stress, and its imbalance can lead to conditions such as Cushing's disease or Addison's disease.

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research EFFECTS OF ADRENOCORTICOTROPIC HORMONE ON BODY GROWTH, VISCERAL PROPORTIONS, AND WHITE BLOOD CELL COUNTS OF NORMAL AND HYPOPHYSECTOMIZED MALE RATS

24 citations , May 1951 in “Endocrinology”

This study describes the effects of adrenocorticotropic hormone injections in rats, specifically detailing their stunted body growth and changes in visceral proportions and hematology.

research Adrenocorticotropic Hormone (ACTH) But Not Alpha-Melanocyte Stimulating Hormone (a-MSH) as a Mediator of Adrenalectomy Induced Hair Growth in Mink

16 citations , April 1998 in “Journal of Investigative Dermatology”

ACTH promotes hair growth in mink, but α-MSH does not.

research Idiopathic isolated adrenocorticotropic hormone deficiency combined with testicular germ cell tumor: Case report

October 2025 in “Medicine”

This case report presents a patient with idiopathic isolated ACTH deficiency and testicular germ cell tumor, with alopecia areata as an initial symptom, suggesting a potential link between these conditions.

research The effect of hormones of the hypothalamic-pituitary-target gland axes in a kidney-yang deficiency syndrome model

11 citations , January 2020 in “World Journal of Traditional Chinese Medicine”

This study used a glucocorticoid-injection model to mimic kidney-yang deficiency syndrome and reported symptoms related to hormonal imbalances in the hypothalamic-pituitary-target gland axes.