research Neuroimmunoregulation of Androgens in the Adrenal Gland and the Skin
This article reviews the regulation of androgens in human skin and adrenals, highlighting their role in skin disorders, but reports no new research findings.
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5 / 1000+ results research Machine learning-based steroid metabolome analysis reveals three distinct subtypes of polycystic ovary syndrome and implicates 11-oxygenated androgens as major drivers of metabolic risk
This study identified three subgroups of women with PCOS with distinct androgen profiles, finding that the subgroup with adrenal-derived androgen excess had the highest insulin resistance and rates of hirsutism and hair loss.
research Androgen excess: a hallmark of polycystic ovary syndrome
This review explores the role of hyperandrogenism, including adrenal-derived 11-oxygenated androgen, in the development of polycystic ovarian syndrome and discusses potential therapeutic strategies targeting androgen excess, without reporting new clinical results.
research The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report
This review discusses the definition of polycystic ovary syndrome proposed by the AE-PCOS Society Task Force, emphasizing hyperandrogenism, ovarian dysfunction, and excluding related disorders, while noting potential variations needing more research.
research Androgen action on human skin – from basic research to clinical significance
This paper reviews the role of androgens in human skin function and the challenges in developing treatments for androgen-associated disorders, reporting no new experimental results.
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5 / 58 resultscommunity Thoughts about ORAL ketoconazole? (pills)
Oral ketoconazole is discussed as a potential hair loss treatment, but it poses significant health risks like liver damage and adrenal insufficiency. Users suggest safer alternatives like topical anti-androgens or spironolactone, emphasizing the importance of consulting a specialist.
community Sugar and Hair loss connections
High sugar diets may worsen hair loss by increasing 5α-reductase activity and androgen levels, especially in women with PCOS. A low sugar diet might reduce scalp DHT levels, similar to finasteride, but genetics also significantly influence hair loss.
community My Theory Of Androgenic Alopecia
Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.
community Finasteride's impact on blood pressure - mechanism of action
Finasteride may cause mild blood pressure-related side effects in less than 10% of users, unlike minoxidil, which has stronger effects. Alternatives like topical ketoconazole and dermarollers are suggested for those concerned about finasteride's side effects.
community Finasteride and Eye Problems: You’re Not Going Crazy
Finasteride can cause dry eyes and vision issues due to its impact on the meibomian glands. Users have mixed experiences, with some experiencing eye discomfort and others having no side effects.
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1 / 801 resultslearn dehydroepiandrosterone
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