January 1988 in “Chemical and Pharmaceutical Bulletin” This study found that ointments containing indomethacin and its calcium salt showed potent anti-inflammatory effects on rat paw edema and arthritis with minimal skin irritation, suggesting potential for clinical use.
32 citations
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January 2022 in “Oxidative Medicine and Cellular Longevity” This study found that cedrol, administered orally, exhibited potential antiarthritic effects in rats by reducing inflammation, oxidative stress, and arthritis severity.
March 2020 in “Section 5: Patient safety and quality assurance” This study found that tofacitinib and baricitinib had an acceptable adverse reaction profile when used to treat rheumatoid arthritis, with similar side effects to those described in their technical data sheets.
1 citations
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November 2025 in “Frontiers in Immunology” This review explores the complex role of the Innate Immune System in rheumatoid arthritis, highlighting gaps in understanding its functions and interactions with the Adaptive Immune System, offering insights into potential biomarkers and therapeutic strategies for this challenging autoimmune condition.
4 citations
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March 2019 in “Journal of Pure and Applied Microbiology” This study investigated the anti-inflammatory effects of a 940nm diode laser in Wistar rats with carrageenan-induced arthritis and found that a 74J/cm² energy density significantly reduced edema and restored function, whereas 171J/cm² neared thermal exposure limits for the skin.