November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reported that adipose stem cell exosomes, combined with microneedling, improved facial skin wrinkles, elasticity, hydration, and pigmentation compared to a placebo, with significant results on the Global Aesthetic Improvement Scale and no serious adverse events noted in treated individuals.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, topical application of adipose stem cell exosomes was found to reduce facial redness in atopic dermatitis patients treated with dupilumab, while improving skin hydration and decreasing inflammation markers over 12 weeks.
2 citations
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August 2024 in “International Journal of Dermatology” This study found that treating patients with androgenetic alopecia using exosomes from adipose tissue stem cells over 24 weeks significantly increased hair density and patient satisfaction without severe adverse effects, suggesting a promising alternative treatment for hair loss.
18 citations
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April 2022 in “Frontiers in bioengineering and biotechnology” This study found that gelatin microspheres delivering adipose-derived stem cells significantly accelerated diabetic wound healing in rats, suggesting a promising approach for enhancing cell-based therapies.
September 2026 in “Journal of Cosmetic Dermatology” This review reports limited evidence suggesting that stem cell-based therapies, particularly using human-derived mesenchymal stem cells and exosomes, may be effective for skin rejuvenation, though results are uncertain due to methodological limitations and variability across studies.