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GlossaryAdaptogens

natural substances that help the body adapt to stress

Adaptogens are natural substances, often derived from plants and herbs, that are believed to help the body resist and adapt to stressors, whether physical, chemical, or biological. They work by modulating the body's stress response and promoting homeostasis, potentially improving overall health and resilience. Examples include ashwagandha, rhodiola, and ginseng.

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research Bibliometric Study of Adaptogens in Dermatology: Pharmacophylogeny, Phytochemistry, and Pharmacological Mechanisms

1 citations , February 2023 in “Drug Design Development and Therapy”

Plant adaptogens may help treat skin diseases and improve skin health, but more research is needed to fully understand how they work.

research Hair Follicle Dermal Cells Differentiate Into Adipogenic and Osteogenic Lineages

268 citations , December 2003 in “Experimental Dermatology”

Hair follicle cells can become fat and bone cells.

research Epidermal Wnt/β-Catenin Signaling Regulates Adipocyte Differentiation via Secretion of Adipogenic Factors

130 citations , March 2014 in “Proceedings of the National Academy of Sciences of the United States of America”

Epidermal Wnt/β-catenin signaling controls fat cell formation and hair growth.

research Cultured Cells From the Adult Human Hair Follicle Dermis Can Be Directed Toward Adipogenic and Osteogenic Differentiation

38 citations , April 2005 in “Journal of Investigative Dermatology”

Human hair follicle cells can become fat and bone cells, useful for therapy.

research Fluoxetine Decreases the Proliferation and Adipogenic Differentiation of Human Adipose-Derived Stem Cells

24 citations , July 2015 in “International Journal of Molecular Sciences”

Fluoxetine may help reduce fat by limiting stem cell growth and fat cell formation.

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community The Big Fat Layer / Remedies: Cetirizine

in Treatment 12 upvotes 5 years ago

Treating hair loss with various remedies, such as Cetirizine and the Big3 complex (minoxidil, finasteride, and RU58841), which have properties like adipogenic, anti-fibrotic and anti-inflammatory. References to research studies are also included.

community When you start Fin for the first time and document progress.

in Satire 409 upvotes 2 years ago

A user's experience with using Fin for hair loss, which includes shedding and regrowth, potential side effects, and the use of supplements, protein, and exercise as additional treatments.

community Can ashwagandha cause hair loss?

in Finasteride/Dutasteride 13 upvotes 4 years ago

Ashwagandha is generally considered safe for hair while on Dutasteride, as its effects on testosterone are minimal and it may reduce anxiety. Some users report positive effects on hair thickness and anxiety reduction when using ashwagandha alongside finasteride.

community Switching from oral to topical finasteride due to mood issues - 4 months post transplant

in General 144 upvotes 9 months ago

The user experienced mental side effects from oral finasteride, such as brain fog and low mood, and switched to topical finasteride combined with minoxidil. They are monitoring mental clarity and hair progress after stopping oral finasteride.

community ~6 years on Fin + 3 years of Min. Seeing zero progress.

in Progress Pictures 228 upvotes 2 months ago

The user has been using finasteride for six years and minoxidil for three years with no noticeable hair regrowth. Suggestions include switching to dutasteride, considering a hair transplant, and trying microneedling.

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