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    Glossary Adaptogen

    Adaptogens are natural substances, often derived from plants, that help the body adapt to stress and promote homeostasis. In the context of hair loss, adaptogens may play a role in reducing stress-related hair shedding and supporting overall hair health by balancing hormonal levels and enhancing resilience to environmental stressors. Key distinguishing characteristics of adaptogens include their ability to normalize physiological functions and their non-specific action, meaning they can benefit various bodily systems rather than targeting a single issue.

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    1. Bibliometric Study of Adaptogens in Dermatology: Pharmacophylogeny, Phytochemistry, and Pharmacological Mechanisms Drug Design Development and Therapy · 2023 · 1 citations
    2. Adaptogenic herbal extracts for stress-induced dermatoses: a narrative review Archives of Dermatological Research · 2026
    3. Hair follicle dermal cells differentiate into adipogenic and osteogenic lineages Experimental Dermatology · 2003 · 268 citations
    4. Epidermal Wnt/β-catenin signaling regulates adipocyte differentiation via secretion of adipogenic factors Proceedings of the National Academy of Sciences of the United States of America · 2014 · 130 citations
    5. Cultured Cells from the Adult Human Hair Follicle Dermis can be Directed Toward Adipogenic and Osteogenic Differentiation Journal of Investigative Dermatology · 2005 · 38 citations
    6. Fluoxetine Decreases the Proliferation and Adipogenic Differentiation of Human Adipose-Derived Stem Cells International Journal of Molecular Sciences · 2015 · 24 citations
    7. Functionally enhanced placenta-derived mesenchymal stem cells inhibit adipogenesis in orbital fibroblasts with Graves’ ophthalmopathy Stem Cell Research & Therapy · 2020 · 20 citations
    8. Megestrol Acetate Increases the Proliferation, Migration, and Adipogenic Differentiation of Adipose-Derived Stem Cells via Glucocorticoid Receptor Stem Cells Translational Medicine · 2015 · 11 citations
    9. DNMT1-mediated methylation inhibits microRNA-214-3p and promotes hair follicle stem cell differentiate into adipogenic lineages Stem cell research & therapy · 2020 · 8 citations
    10. Comparative characterization and osteogenic / adipogenic differentiation of mesenchymal stem cells derived from male rat hair follicles and bone marrow Cell regeneration · 2020 · 6 citations
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