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research The Combination of Stromal Vascular Fraction Cells and Platelet-Rich Plasma Mediates the Inflammatory Process in Deep Dermal Burn Injury.

1 citations , December 2023 in “PubMed”

This study on rats found that combining platelet-rich plasma with stromal vascular fraction cells helped accelerate burn wound healing by affecting inflammatory cell counts and COX-2 expression, with differing impacts observed between acute and sub-acute phases of healing.

research Cutaneous necrosis after injection of polyethylene glycol–modified interferon alfa

26 citations , June 2005 in “Journal of The American Academy of Dermatology”

In this study, pegylated interferon alfa-2b injections led to local cutaneous reactions, including cutaneous necrosis, in patients with hepatitis C and chronic myelocytic leukemia, requiring dose modifications or treatment withdrawal in some cases.

Chapter 20: Advances in Dermatological Treatments

research Chapter 20 Dermatological Agents

4 citations , January 1987 in “Annual reports in medicinal chemistry”

This review discusses recent developments in dermatological treatments for skin conditions such as acne, psoriasis, acute inflammation, and alopecia but reports no new clinical results.

research Acute Stress-Induced Changes in Follicular Dermal Papilla Cells and Mobilization of Mast Cells: Implications for Hair Growth

13 citations , January 2016 in “Annals of Dermatology”

This study found that acute stress in rats inhibits hair growth, likely through increased cortisol levels and activation of the substance P-mast cell pathway.

research Cutaneous wound healing: canine allogeneic ASC therapy

20 citations , June 2020 in “Stem Cell Research & Therapy”

This study found that treating acute and chronic canine skin wounds with adipose-derived mesenchymal stem cells significantly improved healing and reduced inflammation, suggesting potential benefits for human wound care.

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community Everything you ever wanted to know about Pelage Pharma's PP405: how it works and what to expect

126 upvotes 3 months ago

PP405 may encourage earlier hair growth and slightly increase visible hair count but does not reverse hair follicle miniaturization in male pattern baldness. It does not address damage to the dermal papilla or broken Wnt signaling.

community Occipitalis Muscle Tension Theory

13 upvotes 7 months ago

Scalp tension from the occipitalis muscle is theorized to contribute to hair loss, but most believe DHT and genetics are the main causes. Treatments like finasteride and minoxidil are considered more effective than addressing scalp tension.

community How accurate is this picture ??

3084 upvotes 8 months ago

People discussed using finasteride, minoxidil, and dutasteride for hair loss, with mixed results and side effects. Some had positive outcomes, while others experienced issues like libido changes and chose alternatives like hair systems.

community Not only balding at a very young age but also not responding to the meds well.

in Finasteride/Dutasteride 114 upvotes 1 year ago

A young person is experiencing aggressive hair loss and not responding well to minoxidil and finasteride. Suggestions include trying dutasteride, hair systems, lifestyle changes, or considering a wig.

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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