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    GlossaryAcid Value

    measure of free fatty acids in fats or oils

    The Acid Value (AV), also known as Acid Number, is a measure of the amount of free fatty acids present in a fat or oil. It is defined as the number of milligrams of potassium hydroxide (KOH) required to neutralize the free fatty acids in one gram of the substance. This value is important in industries like cosmetics and food, as it indicates the quality and shelf life of the product; higher acid values can suggest degradation or rancidity.

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      community Best Value Minoxidil 5-10% Products in the UK?

      in Minoxidil  2 upvotes 6 months ago
      A user is seeking recommendations for more affordable Minoxidil products in the UK, currently spending £65 per month on 5% liquid and 10% cream with Azelaic Acid. They also inquire about the quality differences between Minoxidil brands.

      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 1 week ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

      community Fats on your Head to Stop Hair Loss?

      in Research/Science  140 upvotes 9 months ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

      community New Latanoprost-Based Formula Used by Hollywood Celebrities

      in Treatment  27 upvotes 1 year ago
      A new Latanoprost-based formula used by Hollywood celebrities to treat hair loss, with the formula containing minoxidil, tretinoin, melatonin, azelaic acid, zinc thymulin, vitamin B6, sandalore and methyl vanillate. It also mentions the potential of offering a combined sublingual minoxidil/oral dutasteride option in the future.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 2 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.