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research Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model

48 citations , September 2020 in “Frontiers in Immunology”

In this study, researchers found that loss of OGG1 in a mouse model of systemic lupus erythematosus increased IFN-driven immune responses and aggravated skin lesions, suggesting a protective role for OGG1 in SLE skin disease.

research Overview of Caffeine Effects on Human Health and Emerging Delivery Strategies

43 citations , July 2023 in “Pharmaceuticals”

This review explores the effects of caffeine on cancer, cardiovascular, immunological, inflammatory, and neurological diseases, including its use in sports, and discusses advancements in caffeine delivery through novel nanocarrier-based formulations.

research Phloroglucinol Enhances Anagen Signaling and Alleviates H₂O₂-Induced Oxidative Stress in Human Dermal Papilla Cells

March 2024 in “Journal of Microbiology and Biotechnology”

This study suggests that phloroglucinol may enhance anagen signaling and reduce oxidative stress-induced damage in human dermal papilla cells, offering a potential therapy for hair loss.

research Anti-cancer properties of olive oil secoiridoid phenols: a systematic review of in vivo studies

104 citations , January 2016 in “Food & Function”

This review found that olive oil phenols may have anti-cancer properties in animal models and some human studies, but further research is needed to confirm these effects in humans.

research ROR2 regulates self-renewal and maintenance of hair follicle stem cells

16 citations , August 2022 in “Nature Communications”

In this study, researchers discovered that ROR2, a Wnt receptor, plays a crucial role in regulating hair follicle stem cell self-renewal and maintenance, compensating for the absence of β-catenin.

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community 8.5 months of finasteride 2 years of Minoxidil and below baseline.

5 upvotes 1 week ago

The user has been using finasteride for 8.5 months and minoxidil for 2 years but is experiencing worsened hair loss. Suggestions include trying dutasteride and considering a hair transplant.

community 8 month on fin and oral min (stopped topical min)

105 upvotes 2 weeks ago

The user has been using 1.25 mg finasteride and 2.5 mg oral minoxidil for 8 months, stopping topical minoxidil and dermastamping after 5 months due to exams, with no side effects reported. They are considering whether to restart topical minoxidil for additional regrowth.

community 8 months finasteride - still shedding ? Should I hop on minox or dut ?

20 upvotes 2 weeks ago

A 29-year-old man has been using finasteride for 8 months but is still experiencing hair shedding and is considering adding minoxidil or switching to dutasteride. Users advise that shedding is normal, suggest continuing finasteride for a year, and recommend consulting a dermatologist before changing treatments.

community 8 months on fin + min this are the results so far

7 upvotes 3 weeks ago

A 19-year-old has been using oral finasteride and topical minoxidil for 8 months with positive results and no side effects. The user believes they would have progressed to Norwood 4 without the medication.

community 8 months of Progress - Oral minoxidil 2.5mg, Dutasteride 0.5mg

648 upvotes 1 month ago

A user shared their 8-month hair regrowth journey using oral minoxidil 2.5mg and dutasteride 0.5mg, showing significant progress and plans to start microneedling with topical minoxidil. The user is happy with the results, despite some remaining hairline issues, and received positive feedback from others.

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