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The Effect of St. John's Wort on the Pharmacokinetics, Metabolism, and Biliary Excretion of Finasteride and Its Metabolites in Healthy Men

research The Effect of St. John's Wort on the Pharmacokinetics, Metabolism, and Biliary Excretion of Finasteride and Its Metabolites in Healthy Men

33 citations , November 2008 in “European Journal of Pharmaceutical Sciences”

St. John's wort increases finasteride metabolism, reducing its effectiveness; use caution when combining them.

research Finasteride

86 citations , July 1993 in “Drugs”

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

research Weekly Treatment with SAMiRNA Targeting the Androgen Receptor Ameliorates Androgenetic Alopecia

3 citations , January 2022 in “Scientific Reports”

A new treatment called SAMiRNA-AR68 increases hair count in people with hair loss, showing similar results to existing treatments but without side effects.

Sulforaphane-Rich Broccoli Sprout Extract Promotes Hair Regrowth in an Androgenetic Alopecia Mouse Model via Enhanced Dihydrotestosterone Metabolism

research Sulforaphane-Rich Broccoli Sprout Extract Promotes Hair Regrowth in an Androgenetic Alopecia Mouse Model via Enhanced Dihydrotestosterone Metabolism

August 2025 in “International Journal of Molecular Sciences”

Broccoli sprout extract may help regrow hair by improving hormone metabolism.

Improvement of Androgenic Alopecia by Extracellular Vesicles Secreted from Hyaluronic Acid-Stimulated Induced Mesenchymal Stem Cells

research Improvement of Androgenic Alopecia by Extracellular Vesicles Secreted from Hyaluronic Acid-Stimulated Induced Mesenchymal Stem Cells

September 2024 in “Stem Cell Research & Therapy”

HA-stimulated stem cell vesicles improved hair growth in male mice with androgenetic alopecia.

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Community Join

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community Progress report for 7 months, with 6500 grafts done.

in Progress Pictures 16 upvotes 1 year ago

A 36-year-old had a hair transplant with 6,500 grafts 7 months ago, took 1.25mg of finasteride every other day for 5 months, and recently switched to 1mg daily along with 5% minoxidil spray. They are considering a touch-up transplant and are seeking advice on their progress and future expectations.

community Why do so many people trash on finasteride?

in Chat 247 upvotes 1 year ago

Finasteride is effective for hair regrowth, especially on the crown, but can cause side effects like reduced libido and erectile dysfunction in some users. Opinions are mixed, with some reporting positive results without side effects and others experiencing significant issues.

community Hair much worse after 6 months?

in Progress Pictures 230 upvotes 2 years ago

A user experienced significant hair loss after 6 months of using 0.5mg finasteride daily. Suggestions from others included trying Dutasteride and Minoxidil, getting professional help from a dermatologist, and addressing high iron levels that could be contributing to the hair loss.

community I am horny as hell due to fin.

in Finasteride/Dutasteride 225 upvotes 2 years ago

Some individuals taking finasteride for hair loss report increased libido and frequent masturbation, with no immediate hair regrowth but darker hair appearance. A dermatologist explains that finasteride may raise testosterone levels temporarily, which could lead to increased sex drive in some people.

community 3 months on low dose Topical Fin + Min

in Progress Pictures 102 upvotes 1 year ago

The user has been using Essengen 6+ (a mix of low-dose topical finasteride and minoxidil) for three months, seeing positive results, especially on the crown area. They also use Nizoral for dandruff and dermaroll weekly.

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