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research 5-Bromo-3,4-dihydroxybenzaldehyde Promotes Hair Growth through Activation of Wnt/β-Catenin and Autophagy Pathways and Inhibition of TGF-β Pathways in Dermal Papilla Cells

7 citations , March 2022 in “Molecules”

This study found that 5-bromo-3,4-dihydroxybenzaldehyde (BDB) promoted hair growth in rat vibrissa follicles by activating Wnt/β-catenin and autophagy pathways and inhibiting the TGF-β pathway in dermal papilla cells.

research Association study reveals a susceptibility locus with male pattern baldness in the Han Chinese population

September 2024 in “Frontiers in Genetics”

In this study, researchers found a significant association between the rs13405699 SNP at 2q31.1 and male pattern baldness among Han Chinese men, suggesting genetic influence on this condition in this population.

research Autophagy Dysfunction: The Kernel of Hair Loss?

May 2024 in “Clinical Cosmetic and Investigational Dermatology”

In this study, researchers reviewed the roles of autophagy and mitophagy in hair follicle cycles, exploring their potential links to hair loss and investigating how manipulating these pathways might offer new therapeutic strategies.

research N6-methyladenosine (m6A)-circHECA from secondary hair follicle of cashmere goats: identification, regulatory network and expression regulated potentially by methylation of its host gene promoter

2 citations , August 2024 in “Animal Bioscience”

This study suggests that m6A-circHECA may influence the physiology of cashmere goats' SHFs both through miRNA pathways and interactions with target proteins, with promoter methylation potentially inhibiting its gene expression.

research Hair Growth-Promoting Effects of Astragalus sinicus Extracts in Human Follicle Dermal Papilla Cells

January 2025 in “Cosmetics”

In this study, the researchers found that Astragalus sinicus extracts improved wound healing, reduced oxidative stress, and activated crucial signaling pathways in dermal papilla cells damaged by dihydrotestosterone, suggesting it may be a promising ingredient for hair loss treatment.

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community How am I doing at 4 months? Topical finasteride 0.3% and minoxidil 6%

in Is this regrowth? 344 upvotes 1 year ago

The user is experiencing positive hair regrowth after four months using a topical serum containing 0.3% finasteride and 6% minoxidil, specifically from the brand Hims. They apply the serum mainly to the hairline and have not observed any side effects.

community 3 months fin/min progress (age 31)

in Progress Pictures 173 upvotes 2 years ago

A user shared their 3-month progress using 1mg oral finasteride daily and 5% topical minoxidil twice daily, along with Pura D’Or anti-thinning shampoo and a scalp massager. They noticed initial worsening but later saw hair follicle recovery.

community 4 months in (1.2mg fin, 3mg min, thick fix shampoo)

830 upvotes 1 year ago

Impressive hair regrowth was achieved in 4 months using 1.2mg finasteride, 3mg minoxidil, and Thick Fix shampoo. No side effects were reported, and the user encouraged others to try these treatments.

community Convinced dad to get into minox 3 months ago and fin 2 months ago

in Is this regrowth? 818 upvotes 2 years ago

A user convinced their 45-year-old dad to use minoxidil and finasteride, resulting in significant hair regrowth. The dad now uses 1mg of finasteride daily and topical minoxidil twice a day, and has also started using 1% ketoconazole shampoo.

community 1mg Finasteride daily for almost 4 years (late 2022 - today)

416 upvotes 6 months ago

The user has been taking 1mg of finasteride daily since late 2022, which has stabilized hair thinning but not significantly regrown hair. They are considering adding minoxidil for potential regrowth, and report no side effects from finasteride.

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